直肠镜下取肠液隐血检测和常规粪便隐血检测的差异分析

Analysis on the difference between occult blood test by collecting intestinal juice under colonoscope and conventional stool occult blood test under colonoscope

目的对比评价直肠镜下取肠液检测隐血和粪便隐血检测,揭示直肠镜下取肠液检测隐血和粪便隐血检测的差异所在。方法对本院1380例健康体检人群行粪便血红蛋白测定以及直肠镜检查和肠液血红蛋白测定,并对结果进行分析。结果体检人群中粪便血红蛋白的阳性率为13.77%,肠液血红蛋白的阳性率为3.12%,查出直肠息肉的有41例。结论粪便隐血检测是消化道出血筛查的重要方法,但是容易受到肛周出血性疾病如痔疮、肛裂的影响出现假阳性。同时因为粪便隐血检查的标本依靠受检者自主排便获得,标本在肠道中存留时间过长,容易受消化酶和肠道细菌作用,或者少量消化道出血与粪便混合不匀,取样不足的情况下容易检测出现假阴性。肠液血红蛋白的检测能避免这些因素的影响,得出不一样的结论。

Objective To compare and evaluate the data of occult blood test by collecting intestinal fluid under colonoscope and stool occult blood test,and to reveal the difference between occult blood test by collecting intestinal fluid under colonoscope and stool occult blood test.Methods A total of1380people receiving physical examination in our hospital were given stool hemoglobin determination,and were also given colonoscopy and intestinal fluid hemoglobin determination.The results were analyzed.Results The positive rate of stool hemoglobin in the physical examination people was13.77%,and the positive rate of intestinal fluid hemoglobin was3.12%.There were41cases with rectal polyps.Conclusion Stool occult blood test is an important method of screening for gastrointestinal bleeding,but is vulnerable to perianal hemorrhagic diseases such as hemorrhoids,anal fissure and other diseases to appear false positive results.At the same time,because the specimens of stool occult blood test are obtained depending on the subjects to defecate dependently,the specimens may be susceptible to digestive enzymes and intestinal bacteria if they stay in the intestine for too long.Or there may be a small amount of gastrointestinal bleeding and uneven mixing of stools,and thus a false negative result may be obtained if the specimens are insufficient.Intestinal fluid hemoglobin test can avoid the impact of these factors,coming into a different conclusion.