布地奈德联合不同浓度氯化钠溶液雾化对婴幼儿肺炎的影响观察

Effect of different concentrations of sodium chloride solution on the efficacy of Budesonide in the treatment of pneumonia of infants

目的探讨不同浓度氯化钠溶液联合布地奈德雾化液对婴幼儿肺炎疗效的影响。方法将72例婴幼儿肺炎患儿分为A组(34例,给予布地奈德加生理盐水雾化)和B组(38例,给予布地奈德加3%氯化钠雾化),观察2组治疗后症状改善状况及临床疗效。结果 2组治疗后咳嗽、咳痰、肺部啰音等症状均在3 d^5 d明显改善,但是B组症状改善和消失时间明显较A组快,住院天数较A组短,差异均有统计学意义(P<0.05)。B组治愈率(68.4%)较高,但是2组整体疗效差异没有统计学意义(P>0.05)。结论小儿肺炎在常规治疗的基础上使用3%的盐水配合布地奈德雾化吸入疗效较好,能够较快地改善咳嗽、啰音等症状体征,提高疗效。

Objective To investigate the effect of different concentrations of Sodium Chloride Solution on the efficacy of budesonide in the treatment of pneumonia of infants.Methods72cases of infantile pneumonia were divided into A group(34cases,treated with budesonide+saline)and group B(38cases,treated with budesonide+3%NaCl),and clinical symptoms of two groups were observed.Results After treatment,cough,expectoration,pulmonary rales and other symptoms of the two groups were significantly improved within3~5d,but and improvement of symptoms disappeared time in group B was significantly faster than in group A,and hospitalization time was shorter than that of group A(P<0.05).The cure rate was higher in group B(68.4%),but there was no significant difference between the two groups(P>0.05).Conclusion On the basis of routine treatment,using budesonide combined with3%saline solution inhalation is effective for children with pneumonia.It can improve symptoms and signs quickly and improve the curative effect.