人参三七茶抗疲劳及免疫调节作用研究

Study on the anti-fatigue and immune-regulation effect of Ginseng and Sanchi Tea

目的探讨人参三七茶的抗疲劳及免疫调节作用。方法给40只小鼠连续灌胃高(人参、三七均0.8g·kg-1)、中(人参、三七均0.4g·kg-1)、低(人参、三七均0.2g·kg-1)剂量的人参三七茶,同时设立空白对照组,成熟小鼠连续灌胃后,以负荷游泳的方法制备疲劳模型,观察小鼠负荷游泳实验,测定小鼠游泳耗竭时间以及血中尿素氮和肝糖原的含量;观察其对淋巴细胞的转化和自然杀伤细胞(NK)活性的影响。结果与空白对照组比较,高、中剂量人参三七茶可明显延长小鼠游泳耗竭时间,高剂量人参三七茶能降低血中尿素氮的含量并增加肝糖原的含量,能够显著提高淋巴细胞的转化和NK细胞的活性。结论人参三七茶对小鼠具有抗疲劳、增强免疫的作用。

Objective To study the anti-fatigue and immune-regulation effect of Ginseng and Sanchi Tea.Methods40mice were continuously gavaged high(Ginseng0.8g·kg-1),middle(Sanchi0.4g·kg-1)and low(Sanchi0.2g·kg-1)doses of Ginseng and Sanchi Tea,and blank control group was also established.After continuously gavaging,the time of exhausting swimming,levels of hepatic and usea nitrogen(BUN),the transformation of lymphocytes and the activity of naturalkiller(NK)cells of the mature mice were measured and observed.Results Compared with the blank control group,the high and middle doses of Ginseng and Sanchi Tea group can prolong the time of exhausting swimming,the high dose of Ginseng and Sanchi Tea group can decrease the level of BUN,increase the levels of glycogen reserve of liver glycogen in the body,improve the transformation of lymphocyte and the activity of NK cell.Conclusion Ginseng and Sanchi Tea has a good effect on anti-fatigue and immuno-enhance.