基于专利分析的世界传统药物创新技术分布与趋势研究

Study on Distribution and Trend of Innovation Technology of World Traditional Drugs Based on Patent Analysis

目的了解世界传统药物的创新技术整体布局与趋势。方法按照国际专利分类法结合关键词检索Innography专利数据库,对2006年1月1日-2016年12月31日世界传统药物相关专利文献进行统计。采用频数统计进行趋势分析、热点分布研究;采用文本聚类、相关性分析进行热点分析;采用Innography专利数据库集成的专利强度分析功能,进行世界传统药物专利强度分布分析;采用趋势图、世界地图、气泡图、树图、文本聚类环形图等可视化图表进行结果展示。结果近年世界传统药物专利申请量呈逐年递增趋势,以中国、韩国、日本和美国为主。创新技术主要集中在药物组合物、生药、提取物、化学成分和健康服务等方面。消化系统疾病、疼痛/发热/炎症、感染、皮肤疾病等为传统药物疗效研究的热点领域。除临床治疗外,传统药物作为化妆品、保健品、膳食补充剂、饮品等新用途也被广泛深度开发。结论世界传统药物专利逐年递增,中国、美国的创新技术世界领先。慢性病、难治病为传统药物治疗的热点领域。传统药物的多种新用途被广泛开发。

Abstract:Objective To analyze the distribution and tends of innovation technology of traditional drugs around the world.Methods Relevant patent literature about world traditional drugs in Innography patent database was retrieved by IPC class numbers combined with keywords.The patents of traditional drugs from January1st,2006to December31st,2016were under statistical analysis.Frequency statistics was used for trend analysis and hot spot distribution;text clustering and correlation analysis were used for hot spot analysis;patent database was used for strength analysis,to analyze the strength of drug distribution of world traditional patent;visual charts were used to display results such as trend charts,bubble charts,tree diagrams,text clustering rings,etc..Results In the recent years,the number of patent applications of traditional drugs has been increasing year by year.China,South Korea,Japan and the United States were the main patent applications/authorized countries.Technology innovation is mainly concentrated in the medicinal compositions,crude drugs,extracts,chemical composition and health care,etc.Digestive system diseases,pain/fever/inflammation,infection,skin diseases and so on are the hot spots of traditional drug therapy.In addition to the use of clinical treatment,traditional drugs have been widely developed as cosmetics,dietary supplements,health products,beverages and other new uses.Conclusion The number of traditional drugs patents is increasing around the world.China and the United States are the leading countries of technology innovation.Chronic and intractable diseases are the hot spots of traditional drug therapy.A variety of new uses of traditional drugs have been developed.