慢性阻塞性肺疾病患者肺结核发生情况

Incidence of Pulmonary Tuberculosis in Patients with Chronic Obstructive Pulmonary Disease

目的分析慢性阻塞性肺疾病患者肺结核发生情况。方法选取2012年6月—2014年2月内蒙古医科大学附属医院收治的慢性阻塞性肺疾病患者160例,其中稳定期慢性阻塞性肺疾病患者80例(A组),急性加重期慢性阻塞性肺疾病患者80例(B组)。两组患者均采用吸入性糖皮质激素治疗6个月,比较两组患者肺结核发生率及治疗前后QOL-100量表评分。结果 B组患者肺结核发生率为67.50%,高于A组的42.50%(P<0.05)。两组患者治疗前后QOL-100量表评分比较,差异无统计学意义(P>0.05);治疗后两组患者QOL-100量表评分均低于治疗前(P<0.05)。结论与稳定期慢性阻塞性肺疾病患者相比,急性加重期慢性阻塞性肺疾病患者肺结核发生风险较高;吸入性糖皮质激素可能导致慢性阻塞性肺疾病患者生活质量降低。

Objective To analyze the incidence of pulmonary tuberculosis in patients with chronic obstructive pulmonary disease.Methods A total of160patients with chronic obstructive pulmonary disease were selected in the Affiliated Hospital of Inner Mongolia Medical University from June2012to February2014,thereinto80cases were stable(served as A group),the other80cases were acute exacerbated(served as B group).Patients of the two groups received inhaled glucocorticoids for6months,incidence of pulmonary tuberculosis,QOL-100scale score before and after treatment were compared between the two groups.Results Incidence of pulmonary tuberculosis of B group was67.50%,was statistically significantly higher than that of A group of42.50%(P<0.05).No statistically significant differences of QOL-100scale score was found between the two groups before or after treatment(P>0.05);after treatment,QOL-100scale score of the two groups were statistically significantly lower than those before treatment(P<0.05).Conclusion Compared patients with stable chronic obstructive pulmonary disease,risk of pulmonary tuberculosis is higher in patients with acute exacerbation of chronic obstructive pulmonary disease;inhaled glucocorticoids may lead to lower quality of life in patients with chronic obstructive pulmonary disease.