2009—2015年女性泌尿生殖道解脲支原体药敏趋势分析

Trend analysis of drug susceptibility about female genitourinary tract of ureaplasma urealyticum in 2009—2015

目的了解该地区女性泌尿生殖道解脲支原体药敏趋势,为临床针对性的用药提供依据。方法记录2009—2015年1 459例女性泌尿生殖道解脲支原体药敏结果,通过统计学分析规律并分析其变化趋势。结果 2009—2015年,女性泌尿生殖道解脲支原体对强力霉素(DOX)、米诺环素(MIN)药敏无变化(均P>0.05);对环丙沙星(CPF)、司帕沙星(SPA)、交沙霉素(JOS)耐药性变化差异无统计学意义(均P>0.05),但有些药敏变化有趋势;对氧氟沙星(OFL)、罗红霉素(ROX)、阿奇霉素(AZI)、克拉霉素(CLA)、壮观霉素(SPE)、螺旋霉素(ASP)、左旋氧氟(LEV)耐药性变化差异有统计学意义(均P<0.05),有些药敏变化有趋势。结论女性泌尿生殖道解脲支原体的药敏会产生变化,应根据药敏情况针对性的合理用药。

Objective To understand the drug sensitive trend of ureaplasma urealyticum about female genitourinary tract,provide the basis for targeted drug use.Methods By ecording1459cases of female genitourinary tract of ureaplasma urealyticu susceptibility results in2009-2015,regularity and the change trend were analyzed through the statistical analysis.Results For female with genitourinary tract of ureaplasma urealyticu,from2009to2015,drug susceptibility to Doxycycline(DOX),Minocycline(MIN)is no change(P[CM(170mm]>0.05),drug resistant of Ciprofloxacin(CPF),Sparfloxacin(SPA),Josamycin(JOS)with no statistical significance(P>0.05).However,there are some susceptibility change trend.Ofloxacin(OFL),Roxithromycin(ROX),Azithromycin(AZI),Clarithromycin(CLA),Spectinomycin(SPE),Acetylspramycin(ASP),Levofloxacin(LEV)drug-fast change difference was statistically significant(P<0.05),there are some susceptibility change trends.Conclusion Drug susceptibility of female genitourinary tract with ureaplasma urealyticum will change,which should be considered for drug rational use.