老年人群缺血性脑卒中危险因素综合干预的效果观察

Effect of Comprehensive Intervention on Risk Factors of Ischemic Stroke in Elderly Patients

目的观察研究采取综合预防措施干预老年人群缺血性脑卒中危险因素的应用效果。方法将86例具备缺血性脑卒中危险因素的老年人随机分为观察组和对照组各43例,观察组给予一级预防干预措施,对照组仅给予随访观察,比较入组6个月后两组患者血脂指标变化;将146例缺血性脑卒中老年患者随机分为观察组和对照组,各73例,观察组给予二级预防干预措施,对照组仅给予随访观察,比较12个月后两组神经功能状况,选用卒中影响量表(SIS)评定。结果一级预防观察组甘油三酯(TG)、血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)较干预前降低,高密度脂蛋白胆固醇(HDL-C)较干预前升高(P<0.05),对照组入组前后无明显变化(P>0.05);二级预防观察组交流、手动能力、运动功能、日常生活活动能力评分较干预前改善,且改善程度均明显优于对照组(P<0.05),生活质量提升明显。结论对老年人群采用综合预防干预措施能较好地降低缺血性脑卒中的患病风险,并可有效改善缺血性脑卒中患者的生活质量。

Objective To observe the effect of comprehensive preventive measures on the risk factors of ischemic stroke in elderly patients. Methods A total of 86 elderly patients with ischemic stroke risk were randomly divided into the intervention group and the control group,each with 43 cases.The intervention group was given primary prevention intervention,and the control group was only given follow-up observation.The variation of the blood lipid index of the two groups was compared after 6 months.A total of 146 patients with ischemic stroke were randomly divided into the intervention group and the control group,each with 73 cases.The intervention group was gave secondary prevention intervention measures,and the control group was gave only follow-up observation.The neurofunctional status of patients estimated by the Stroke Impact Scale(SIS)in the two groups after 12 months was compared. Results In the primary prevention intervention group,TG,TC,LDL-C decreased before intervention,and HDL-C increased before intervention,and the differences were statistically significant(P<0.05).There was no significant difference in the control group(P>0.05).The communication,manual ability,motor function and ADL score of secondary prevention intervention group were significantly better than those in the control group(P<0.05),and the quality of life was significantly improved. Conclusion Comprehensive preventive interventions for the elderly can reduce the risk of ischemic stroke.It can effectively improve the quality of life of patients with ischemic stroke.