不良妊娠结局与TORCH感染相关性的临床探析

Clinical Analysis of the Relationship between Adverse Pregnancy Outcome and TORCH Infection

目的探究不良妊娠结局与TORCH感染的相关性。方法选取2013年10月~2015年10月来本院进行孕期检查的孕妇1 892例,对所有孕妇的临床资料进行回顾性分析。所有孕妇均按妊娠结局分为正常妊娠组1 788例、不良妊娠组104例。对两组孕妇TORCH感染情况和孕妇脐血TORCH感染情况进行检测,并作对比分析。结果所有孕妇中共35例TORCH-IgM检测阳性,占1.85%(35/1 892);而不良妊娠组TORCH-IgM检测阳性率高于正常妊娠组,差异有统计学意义(P<0.05)。所有孕妇中,共22例TORCH-IgG检测阳性,占1.16%(22/1 892);而不良妊娠组TORCH-IgG检测阳性率高于正常妊娠组,差异有统计学意义(P<0.05)。所有孕妇中,共293例进行脐血诊断,9例TORCH-IgM检测阳性,占3.07%(9/293);而不良妊娠组TORCH-IgM检测阳性率高于正常妊娠组,差异有统计学意义(P<0.05)。所有孕妇中,共293例进行脐血诊断,5例TORCH-IgG检测阳性,占1.71%(5/293);而不良妊娠组TORCH-IgG检测阳性率高于正常妊娠组,差异有统计学意义(P<0.05)。结论孕妇不良妊娠结局与TORCH感染具有相关性,而孕妇及新生儿体内均有发生TORCH感染的可能性,临床应将TORCH检查作为常规产前检查项目,做到早诊断、早治疗,改善妊娠结局。

Objective This study aim to explore the correlation between adverse pregnancy outcome and TORCH infection.Methods 1 892 pregnant women were enrolled in our hospital from October 2013 to October 2015,and the clinical data of all pregnant women were retrospectively analyzed.All pregnant women were divided into normal pregnancy group according to pregnancy outcome group 1 788 cases,104 cases of adverse pregnancy group.TORCH infection in pregnant women from two group were detected and compared.Results TORCH-IgM was positive in all the pregnant women,accounting for 1.85%(35/1 892).The positive rate of TORCH-IgM in the adverse pregnant group was higher than that in the normal pregnancy group(P<0.05).The positive rate of TORCH-IgG in all pregnant women was 1.16%(22/1 892),but the difference was statistically significant(P<0.05).In all pregnant women,293 cases were diagnosed with umbilical cord blood,9 cases of TORCH-IgM positive,accounting for 3.07%(9/293);and adverse pregnancy group TORCH-IgM positive rate was higher than the normal pregnancy group,the difference was statistically significant(P<0.05).The positive rate of TORCH-IgG was 1.71%(5/293),while the positive rate of TORCH-IgG in the adverse pregnant group was higher than that in the normal pregnancy group(P<0.05),and the difference was statistically significant(P<0.05).Conclusion There is a significant correlation between the adverse outcome of pregnant women and TORCH infection,and the possibility of TORCH infection in both pregnant women and newborns.TORCH should be used as routine prenatal examination,early diagnosis,early treatment and improvement of pregnancy ending.