针刺联合参松养心胶囊治疗频发室性早搏疗效及对室早频数、指数的影响

Acupuncture Combined with Shensong Yangxin Capsule in the Treatment of VPB:Study of Frequency and Index of VPB

目的:探讨针刺联合参松养心胶囊治疗频发室性早搏及其对室早频数、指数的影响。方法:收集我院收治的气阴两虚络阻型频发室性早搏患者68例,随机分为对照组和试验组,各34例,对照组予以门冬氨酸钾镁片日3次口服治疗;试验组在对照组的基础上采取针刺联合参松养心胶囊的治疗方法,两组患者均治疗4周。治疗结束后,比较两组患者的临床疗效以及室早频数、指数、Tp-e间期指标。结果:治疗后两组患者的Tp-e间期明显缩短,室早频数降低,室早指数提高,中医证候积分降低(P<0.05);与对照组相比,试验组临床总有效率较高,治疗后Tp-e间期缩短,室早频数降低,室早指数提高,中医证候积分降低(P<0.05)。结论:针刺联合参松养心胶囊治疗气阴两虚络阻型频发室性早搏能够显著改善临床疗效,提高室早指数,下调室早频数,缩短Tp-e间期,降低发生恶性心律失常的几率,改善心功能。

Objective:To explore the effect of acupuncture combined with Shensong Yangxin capsule in the treatment of frequent ventricular premature beats(VPB)and to assess its influence to VPB frequency and relative index.Methods:68 patients with frequent VPB were randomly divided into the control group and the observation group,with 34 cases in each group.The control group was treated with Potassium Aspartate and Magnesium Aspartate;on which basis,the observation group was also treated with Shensong Yangxin capsule.After four weeks of the treatment,clinical efficacy,frequency and index of VPB,and index of Tp-e interval were compared between the two groups.Results:Tp-e interval was significantly shortened,and frequency of VPB was decreased,index of VPB was increased,and TCM syndrome integral was decreased(P<0.05),of which the observation group was superior to the control group.Conclusion:The therapy of acupuncture combined with Shensong Yangxin capsule can significantly improve the clinical curative effect on VPB with the pattern of deficiency of both qi and yin,it can increase the index of VPB,down-regulate frequency of VPB,shorten T-p interval;it can reduce the risk of malignant arrhythmia and improve heart function.