岭南山竹子化学成分及活性研究进展

Research Advance in Chemical Constituents and Pharmacological Activities of Garcinia oblongifolia

岭南山竹子(Garcinia oblongifolia)是藤黄科藤黄属乔木,为中国南部一种著名的药用植物。本文总结出从岭南山竹子的不同部位分离到的120个化合物,其中,苯甲酮类、口山酮类是该植物的主要化学成分,具有抗炎、抗病毒、抗癌等活性。近年来有关岭南山竹子的研究主要集中在不同部位的化学成分,及其主要活性;而其作用机理、生物合成途径以及相关产品开发等方面则有待进一步深入探究。本文系统地总结分析近10年的岭南山竹子相关研究成果,为进一步研究与开发该植物资源提供线索。

Garcinia oblongifolia,an arbor in the family Clusiaceae,is a famous medicinal plant in south China.The local people use it as herbal medicine for the treatment of indigestion,cacochylia,bleeding,periodontitis,stomatitis and reducing the fever.In total,120 compounds had been isolated from G.oblongifolia,including benzophenones,xanthones,triterpenes,steroids,etc.Benzophenones and xanthones are the main constituents in G.oblongifolia,distributing in different parts of the plant,which showed strong biological activities of anti-inflammatory,anti-virus,anti-cancer,etc.These years,most researchers were focusing on the chemical components of different parts and their activities,and to explore the main active ingredient.However,its active mechanism,biosynthetic pathway and product development need to be further explored.This review summarizes and analyzes the research results in recent 10 years,which may provide information for further research and development.