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培美曲塞或多西他赛联合顺铂治疗晚期肺腺癌的疗效观察 被引量:2

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摘要 目的观察培美曲塞或多西他赛联合顺铂治疗晚期肺腺癌的疗效及毒副反应。方法选取2012年1月至2014年12月肿瘤科收治的49例晚期肺腺癌患者,25例应用培美曲塞联合顺铂化疗,设为观察组,并与同期24例应用多西他赛联合顺铂化疗的患者作为对照组。观察比较两组患者的近期疗效和不良反应。结果培美曲塞组总有效率为36%,多西他赛组总有效率为30.4%,2组比较差异无统计学意义。最常见的毒副反应是骨髓抑制和胃肠道副反应,其中骨髓抑制两组间比较有统计学意义(P<0.05)。结论培美曲塞联合顺铂治疗晚期肺腺癌疗效肯定,安全性较高。
机构地区 靖江市人民医院
出处 《泰山医学院学报》 CAS 2018年第2期204-205,共2页 Journal of Taishan Medical College
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