应用成人10年患ASCVD风险评估方法对他汀治疗获益人群的横断面研究

A cross-section study of benefiting people with statin therapy by application of 10-year ASCVD risk assessment method for adults

目的应用成人10年患动脉粥样硬化心血管疾病(atherosclerotic cardiovascular disease,ASCVD)风险评估方法对社区居民进行横断面研究,进而探索4种他汀治疗获益人群的具体情况。方法应用2013年美国心脏病学会/美国心脏协会(ACC/AHA)推荐的风险评估方法,对3 516例资料完整的参检者进行分析,按照研究需要计算其中1 891例参检者的10年患ASCVD的风险,进而了解本社区4种他汀治疗获益人群的分布情况及10年患ASCVD风险≥7.5%人群的整体情况。结果本社区4种他汀治疗获益人群751例、10年患ASCVD风险≥7.5%者418例,分别占总入选人数的21.36%和11.89%。10年患ASCVD风险≥7.5%者中,60~69岁者所占比例最高,达49.1%。男性ASCVD评分显著高于女性,差异有统计学意义(P<0.05)。结论社区成人能够从他汀治疗中获益及10年患ASCVD风险≥7.5%者比例较高,且男性风险评分高于女性。

Objective To carry out a cross-section study in community resident by application the 10-year atherosclerotic cardiovascular disease(ASCVD)risk assessment method and then to explore the situation of 4 statin benefit groups.Methods Application of the risk assessment mothod was recommended by ACC/AHA in 2013.A total of 3 516 individuals with integrated data were studied.1 891 individuals were calculated for the 10-year ASCVD risk.Then the distribution of 4 statin benefit groups and the situation of an estimated 10-year ASCVD risk of 7.5% or higher were respectively found.Results Seven hundred and fifty-one patients were benefited from four statin treatments in the community.There were 418 cases with 10 years the risk of ASCVD more than 7.5%.These people accounted for 21.36% and 11.89% of the total number of candidates.In these 10 years the risk of ASCVD≥ 7.5%,60-69 years of age accounted for the highest proportion of 49.1%.The score of ASCVD in males was statistically higher than that in females(P<0.05).Conclusion The prevalence of statin benefit community individuals and 10-year atherosclerotic ASCVD risk of 7.5% or higher in adult were very high.The score of risk estimation in male was more serious than in female.