18F-FDG PET/CT双时显像对老年患者肝细胞肝癌诊断准确性的影响

Influence of ^(18)F-FDG PET/CT dual time imaging on the diagnostic accuracy of hepatocellular carcinoma in elderly patients

目的:探讨^(18)F-FDG PET/CT诊断老年患者肝细胞肝癌方面,不同时相内产生的不同表现,确定出是否可以提高肝癌诊断的准确性。方法:分别在两家医院共选取120例病例,^(18)F-FDG PET/CT检查后,行肝部手术,取病理证实,分肝癌组和良性病变组。分别计算早期及延迟期病灶的最大标准摄取值(SUVmax)和滞留指数,以及病灶SUVmax与肝脏本底SUVmax的比值(T/N)。分析肝癌组和良性病变组病灶的变化规律。结果:所选病例中肝癌组早期及延迟相SUVmax间差异具有统计学意义,良性病变组早期及延迟相SUVmax无统计学意义。肝癌组T/N比值在早期及延迟相也存在显著差异,良性病变组早期及延迟相T/N比值间均无统计学意义。两组滞留指数差异没有统计学意义。结论:^(18)F-FDG PET/CT双时相显像可以提高肝脏细胞癌诊断的准确性。

Objective:To investigate the different manifestations of 18 F-FDG,PET/CT in the diagnosis of hepatocellular carcinoma(HCC)in elderly patients,and to determine whether it can improve the accuracy of HCC diagnosis.Methods:Two hospitals were selected respectively in 120 cases,with pathological confirmation.included liver cancer group and benign lesion group.After 18 F-FDG PET/CT for liver surgery was underwent,the maximum standard uptake value(SUV max)and retention index of the lesions in the early and delayed phases were calculated,and the ratio of the lesion SUV max to the liver basal SUV max(T/N)was calculated.The change of lesion in HCC group and benign lesion group was analyzed.Results:The difference between the early stage and the delayed phase of SUV max in the HCC group was statistically significant.There was no significant difference in the benign lesion group between the early stage and the delayed phase SUV max.The ratio of T/N in HCC group was significantly different between the early stage and the delayed phase.There was no significant difference in the ratio of T/N between the early stage and the delayed phase in the benign lesion group.The difference of retention index between the two groups was not statistically significant.Conclusion:18 F-FDG,PET/CT dual phase imaging can improve the accuracy of the diagnosis of hepatocellular carcinoma.