经鼻高流量鼻导管湿化氧疗治疗中老年重症顽固性肺炎合并呼吸衰竭的疗效

Effect of pernasal high-flow nasal catheter wet oxygen therapy on treating middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure

目的研究分析经鼻高流量鼻导管湿化氧疗治疗中老年重症顽固性肺炎合并呼吸衰竭的疗效及对患者生存质量的影响。方法选取本院接受诊治的100例重症顽固性肺炎合并呼吸衰竭中老年患者作为研究对象,根据随机数表法分为对照组、研究组,各50例。对照组患者接受经鼻持续正压通气疗法治疗,研究组患者接受经鼻高流量鼻导管湿化氧疗治疗。比较2组患者治疗后临床症状消失时间、住院时间及治疗效果、生存质量。结果研究组患者发绀、肺部啰音、气促、三凹征消失时间及住院时间均低于对照组,差异有统计学意义(P<0.05);研究组治疗总有效率(92.0%)高于对照组的(74.0%),差异有统计学意义(P<0.05);治疗后,研究组患者社会关系、环境、心理、生理评分均高于对照组,差异有统计学意义(P<0.05)。结论经鼻高流量鼻导管湿化氧疗治疗中老年重症顽固性肺炎合并呼吸衰竭效果显著,能有效缓解临床症状及体征,改善患者生存质量。

Objective To study the effect of pernasal high-flow nasal catheter wet oxygen therapy for middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure and its effect on quality of life.Methods A total of 100 elderly patients with severe refractory pneumonia complicated with respiratory failure were enrolled in our hospital,and were divided into control group and study group according to the random number table method,with 50 cases in each group.The patients in the control group received pernasal continuous positive pressure ventilation therapy,and the patients in the study group received nasal high-flow nasal catheter wet oxygen therapy.The disappearance time of clinical symptoms,hospitalization time,treatment effect and survival quality were compared between the two groups after treatment.Results The study group had lower disappearance time in cyanosis,lung rales,shortness of breath,three incarads and hospital stay than the control group(P<0.05).The total effective rate was higher than that of the control group(92.0%vs.74.0%,P<0.05).After the treatment,the social,environmental,psychological and physiological scores of the study group were higher than that of the control group,and the differences were statistically significant(P<0.05).Conclusion Pernasal high-flow nasal catheter wet oxygen therapy in the treatment of severe refractory pneumonia patients with respiratory failure has significant efficacy,and it can effectively relieve clinical symptoms and signs,and improve patients'quality of survival.