卵巢癌患者紫杉醇、白蛋白联合顺铂治疗的针对性护理

Effect of targeted nursing for ovarian cancer treated by paclitaxel albumin combined with cisplatin

目的探讨针对性护理对紫杉醇白蛋白联合顺铂治疗卵巢癌效果的影响。方法选择行紫杉醇白蛋白联合顺铂治疗的卵巢癌患者124例,随机分为对照组与研究组各62例。对照组采取常规化疗护理措施,研究组在对照组基础上采取针对性护理干预措施。观察对比2组患者近期疗效、化疗不良反应、病灶1年内的转移率与生存率。结果 2组近期疗效对比中,研究组72.58%高于对照组53.23%(P<0.05);研究组过敏反应、肝肾毒性、恶心呕吐、静脉损伤的发生率均低于对照组(P<0.05);研究组1年内病灶转移率为12.90%低于对照组29.03%(P<0.05),生存率64.52%高于对照组45.16%(P<0.05)。结论针对性护理对紫杉醇白蛋白联合顺铂治疗卵巢癌的效果具有促进作用,值得临床推广。

Objective To investigate the effect of targeted nursing for ovarian cancer treated by paclitaxel albumin combined with cisplatin.Methods A total of 124 patients with ovarian cancer treated with paclitaxel albumin and cisplatin in our hospital were randomly divided into control group and study group,with 62 cases in each group.The control group received routine nursing measures for chemotherapy,while the study group took targeted nursing intervention on the basis of the control group.The short-term clinical outcomes,side effects of chemotherapy,metastasis rate and 1 year survival rate were observed and compared between the two groups.Results The short-term clinical outcomes in the study group was 72.58%,which was higher than 53.23%in the control group(P<0.05).The incidence of anaphylaxis,liver and kidney toxicity,nausea and vomiting,and venous injuries in the study group were lower than that in the control group(P<0.05).The 1 year metastasis rate of the study group was 12.90%,which was lower than 29.03%in the control group,and the survival rate was 64.52%,which was higher than 45.16%in the control group(P<0.05).Conclusion Targeted nursing can significantly promote the effect of paclitaxel albumin combined with cisplatin in the treatment of ovarian cancer,and it is worthy of clinical promotion.