胰岛素样生长因子结合蛋白相关蛋白1与疾病关系的新进展

New progress of the relationship between IGFBPrP1 and diseases

胰岛素样生长因子结合蛋白相关蛋白1(insulin-like growth factor binding protein-related protein 1,IGFBPr P1)属于IGFBP超家族中的一员,是一种分泌蛋白,在细胞增殖、黏附、衰老、凋亡等进程中起重要作用,与恶性肿瘤、肝纤维化等多种疾病关系密切。

Insulin-like growth factor binding protein-related protein 1(IGFBPrP1)is a secreted protein belonging to the insulin-like growth factor binding proteins(IGFBPs)super family,which plays an important role in cell proliferation,adhesion,senescence,apoptosis.IGFBPrP1 has an intimate relationship with some diseases including malignant tumor and liver fibrosis.