平肝涤痰通络汤联合常规治疗对脑梗死恢复期患者的临床疗效

Clinical effects of Pinggan Ditan Tongluo Decoction combined with routine treatment on cerebral infarction patients in the recovery period

目的探讨平肝涤痰通络汤(天麻、钩藤、石菖蒲等)联合常规治疗对脑梗死恢复期患者的临床疗效。方法 116例患者随机均分为观察组与对照组,对照组采用常规治疗,观察组采用平肝涤痰通络汤联合常规治疗。2组疗程均为4周。结果观察组总有效率91.38%,显著高于对照组(75.86%)(P<0.05)。治疗后,2组甘油三酯、总胆固醇、神经功能缺损程度评分显著下降,观察组显著低于对照组(P<0.05);2组日常生活活动能力评分显著增加,观察组显著高于对照组(P<0.05);2组斑块面积、内中膜厚度(IMT)、全血黏度高切(WHV)、全血黏度低切(WLV)、血浆黏度(PV)水平显著降低,观察组显著低于对照组(P<0.05)。2组均未见明显不良反应。结论平肝涤痰通络汤联合常规治疗对脑梗死恢复期患者有显著临床疗效。

AIM To investigate the clinical effects of Pinggan Ditan Tongluo Decoction(G astrodiae R h iz o m a,R a m u lu s U ncariae c u m Uncis y A cori tata rin o w ii R h izo m a,etc.)combined with routine treatment on patients for cerebral infarction recovery.METHODS One hundred and sixteen patients were randomly and equally divided into observation group for Pinggan Ditan Tongluo Decoction combined with routine treatment and control group for routine treatment,and the respective intervention went on for four weeks.RESULTS The observation group displayed a significantly higher general efficiency rate than the control group(91.3 8%to 75.86%,P<0.05);significant group difference in triglyceride,total cholesterol and scores for neural function defect degree decrease with the observation group took a lead(P<0.05)although both groups yielded remarkable lowered values after the treatment(P<0.05).A nd the observation group demonstrated its overall superiority than the control group even if evaluated by the scores for daily living activity(P<0.05),which were significantly higher than the value prior to the administration(P<0.05);and the plaque area,intima-media thickness(IMT),and levels of whole high viscosity(WHV),whole low viscosity(WLV),plasma viscosity(PV)(P<0.05),which were significantly lowered after the treatment(P<0.05).No obvious adverse reactions were observed in both groups.CONCLUSION Pinggan Ditan Tongluo Decoction combined with routine treatment has significantly positive clinical effects on cerebral infarction patients in the recovery period.