期刊文献+

氮酮对6-姜酚透皮吸收的影响 被引量:6

Effect of azone on transdermal absorption of 6-gingerol
下载PDF
导出
摘要 目的研究氮酮对6-姜酚透皮吸收的影响。方法采用TP-6卧式扩散池进行体外透皮扩散试验。选择离体大鼠皮肤作为渗透屏障,考察不同体积分数乙醇、氮酮对6-姜酚渗透性能的影响。结果 30%乙醇、3%氮酮对6-姜酚均有显著促渗透作用。结论本研究可为含6-姜酚经皮给药系统的制备提供依据。 AIM To study the effect of azone on transdermal absorption of 6-gingerol.METHODS In vitro transdermal diffusion test was performed by TP-6 horizontal diffusion pool.In vitro rat skins were selected as permeation barrier,the effects of different concentrations of ethanol and azone on permeation performance of 6-gingerol were investigated.RESULTS Both 3 0%ethanol and 3%azone contributed to the significant permeation enhancement of 6-gingerol.CONCLUSION This research can provide reference for the preparation of transdermal drug delivery systems containing 6-gingerol.
作者 孙权 李冰 王星 祝妍 王星皓 陈再兴 SUN Quan;LI Bing;WANG Xing;ZHU Yan;WANG Xing-hao;CHEN Zai-xing(School of Pharmacy,China Medical University,Shenyang 110122,China)
出处 《中成药》 CAS CSCD 北大核心 2018年第3期583-586,共4页 Chinese Traditional Patent Medicine
关键词 氮酮 6-姜酚 透皮吸收 azone 6-gingerol transdermal absorption
  • 引文网络
  • 相关文献

参考文献13

二级参考文献107

共引文献355

同被引文献71

引证文献6

二级引证文献17

;
使用帮助 返回顶部