期刊文献+

血液透析患者以普通肝素抗凝致血小板减少的药学监护 被引量:6

下载PDF
导出
摘要 目的为临床安全有效治疗肝素诱导的血小板减少症(HIT)提供思路。方法参与治疗1例以普通肝素抗凝的血液透析患者出现血小板减少的病例,通过查阅资料,协助医生判断药物性血小板减少并明确其诊断标准,参与应对方案的设计,建议医生尝试低分子肝素透析抗凝,做好血小板下降的防范准备,并建议明确原因,送检HIT抗体。结果治疗有效,患者血小板维持在正常范围,病情稳定出院。结论临床药师通过参与本例患者的治疗过程,协助医生参与患者病史收集、用药史的梳理与整合,在该患者的诊疗过程中做到了及时发现问题并解决问题。
出处 《医药导报》 CAS 北大核心 2018年第4期489-491,共3页 Herald of Medicine
  • 相关文献

参考文献3

二级参考文献26

  • 1周平,李法琦.常用抗血小板和抗凝药物在心脑血管疾病中的应用[J].心血管病学进展,2004,25(5):338-341. 被引量:10
  • 2Warkentin TE, Greinacher A. Heparin-induced thrombocytopenia: recognition, treatment, and prevention: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest, 2004,126(3 Suppl) :311S-337S.
  • 3Kelton JG, Hursting M J, Heddle N, et al. Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibition. Blood Coagul Fibrinolysis, 2008, 19:471-475.
  • 4Kejariwal D. Heparin-induced thrombocytopenia: a complication of thromboprophylaxis. J Bone Joint Surg Br, 2006,88:392-393.
  • 5Ahmed I, Majeed A, Powell R. Heparin induced thrombocytopenia: diagnosis and management update. Postgrad Med J, 2007,83:575-582.
  • 6Suvarna S, Espinasse B, Qi R, et al. Determinants of PF4/ heparin immunogenicity. Blood, 2007,110:4253-4260.
  • 7Warkentin TE, Sheppard JA, Sigouin CS, et al. Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia. Blood ,2006,108:2937-2941.
  • 8Paparella D, Scrascia G, Galeone A, et al. Formation of anti- platelet factor 4/heparin antibodies after cardiac surgery: influence of perioperative platelet activation, the inflammatory response, and histocompatibility leukocyte antigen status. J Thorac Cardiovasc Surg, 2008,136 : 1456-1463.
  • 9Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med, 1995,332: 1330-1335.
  • 10Weiss BM, Shumway NM, Howard RS, et al. Optical density values correlate with the clinical probability of heparin induced thrombocytopenia. J Thromb Thrombolysis, 2008,26:243-247.

共引文献31

同被引文献56

引证文献6

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部