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4-异丙基-3-甲磺酰基苯甲酸甲酯的合成工艺研究 被引量：1

Study on the Synthesis of 4-isopropyl-3-methyl Sulfonyl Benzoate
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摘要 本文利用5-羟基-2-异丙基苯亚磺酸与硫酸二甲酯合成了目标化合物。重点考察了反应温度、反应时间、溶剂用量等影响因素,优化了合成工艺。 In this paper,the target compounds were synthesized by using 5-hydroxyl-2-isopropylbenzene sulfonic acid and two methyl sulfate.The influence factors such as reaction temperature,reaction time and solvent amount were investigated to discuss the synthesis process.
作者 袁琳 Yuan Lin(Laboratory of Drug Synthesis,Jilin Institute of Materia Medica,Changchun　130061,China)
机构地区 吉林省药物研究院药物合成室
出处 《山东化工》 CAS 2018年第5期15-16,共2页 Shandong Chemical Industry
关键词 5-羟基-2-异丙基苯亚磺酸 硫酸二甲酯 合成 5-hydroxyl-2-isopropylbenzene sulfonic acid two methyl sulfate synthesis
分类号 TQ245.24 [化学工程—有机化工]
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  • 1Burckhardt G, Di Sole F, Helmle-Kolb C .The Na^+/H^+ exchanger gene family [J]. J Nephrol, 2002, 15(Suppl 5) :S3.
  • 2Counillon L,Pouyss gur J. The expanding family of eucaryotic Na^+ /H^+ exchangers [J].JBiol Chem, 2000,275:1.
  • 3Moe OW. Acute regulation of proximal tubule apical membrane Na + /H^+ exchanger NHE-3: role of phosphorylation , protein trafficking ,and regulatory factors[ J ]. J Am Soc Nephrol , 1999,10:2412.
  • 4Baird NR, Orlowski J, Szab EZ, et al. Molecular cloning, Genomic organization, and functional expression of Na +/H + exchanger isoform 5(NHE5)from human brain [J].J Biol Chem,1999,274:4377.
  • 5Numata M, Petrecca K, Lake N, et al. Identification of a mitochondrial Na(+)/H(+) exchanger[J]. J Biol Chem,1998,273:6951.
  • 6Brett CL, Wie Y, Donowitz M, et al. Human Na +/H + exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria [J] .Am J Physiol,2002,282 :C1031.
  • 7Numata M, Orlowski J. Molecular cloning and characterization of a novel Na^+/H + exchanger localized to the trans-Golgi network [ J]. J Bil Chem, 2001,276:17387.
  • 8Goyal S, Vanden-Heuvel G, Aronson PS. Renal expression of novel Na^+/H^+ exchanger isoform NHE-8 [J] .Am J Physiol, 2003,284:F467.
  • 9Laeckmann D, Rogister F, Vdejardin J, et al. Synthesis and biological evaluation of aroylguanidines related to amiloride as inhibitors of the human platelet Na^+/H^+ exchanger [J]. BioorgMed Chem,2002,10:1793.
  • 10Masereel B, Pochet L, Laeckmann D. An overiew of inhibitors of Na^+/H^+ exchanger [J]. Eur J Med Chem ,2003,38:547.

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山东化工
2018年 第5期

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