酒精相关性股骨头坏死的发病特征分析

Analysis of characteristics of onset of alcohol-related osteonecrosis of femoral heads

目的:分析酒精相关性股骨头坏死的发病特征。方法:从电子病历系统导出2009年5月至2016年12月在中国中医科学院望京医院骨关节三科住院治疗的股骨头坏死患者中病因为酒精相关因素者的病历资料,提取患者的性别、年龄、发病部位、病程、饮酒年限、每周饮酒量、每周饮酒次数、国际骨循环研究会(Association Research Circulation Osseous,ARCO)分期及中医证型等信息进行分析。结果:2009年5月至2016年12月中国中医科学院望京医院骨关节三科共收治1249例股骨头坏死患者,其中病因为酒精相关因素者445例,最终纳入402例。以男性患者为主(401例),年龄多在31~50岁(280例),双侧发病者多见(281例),病程多在6个月以内(301例),ARCO分期多属于Ⅲ期(220例),中医证型以经脉痹阻型为主(219例),饮酒年限6~20年者所占比例最大(277例),每周饮酒量多在501~2000 mL(231例),大部分患者每周饮酒次数≥7次(237例)。结论:酒精相关性股骨头坏死的发病特征包括男性、年龄31~50岁、饮酒年限6~20年、每周饮酒501~2000 mL、每周饮酒7次以上、双侧发病、病程≤6个月、ARCO分期多为Ⅲ期、中医证型多为经脉痹阻型。

Objective:To analyse the characteristics of onset of alcohol-related osteonecrosis of femoral heads(ONFH).Methods:The medical records of patients with alcohol-related ONFH who were treated in the third osteoarticular department of Wangjing Hospital of China Academy of Chinese Medical Sciences from May 2009 to December 2016 were exported from the electronic medical record system.The patients’information including gender,age,diseased region,disease course,total drinking time,weekly alcohol consumption,weekly drinking time,clinical stage of ONFH issued by Association Research Circulation Osseous(ARCO)and TCM type of SYMPTOM COMPLEX were extracted and analysed.Results:A total of 1249 patients with ONFH were treated in the third osteoarticular department of Wangjing Hospital of China Academy of Chinese Medical Sciences from May 2009 to December 2016,in which 445 cases with ONFH caused by alcohol-related factors were found,and 402 cases were included in the final analysis.The patients consisted mainly of male(401)and ranged in age from 31 to 50 years(280).Most patients got bilateral ONFH(281)and the disease courses were mainly less than 6 months(301).The ONFH mainly belonged to ARCO phaseⅢ(220),and the TCM type of SYMPTOM COMPLEX were dominated by the type of CHANNELS STAGNATION(经脉痹阻)syndrome(219).The majority of patients ranged in total drinking time from 6 to 20 years(277)and in weekly alcohol consumption from 501 to 2000 ml(231),and most patients drank at least seven times a week(237).Conclusion:The characteristics of onset of alcohol-related ONFH mainly include male,31-50 years of age,6-20 years of total drinking time,501-2000 ml of weekly alcohol consumption,≥7 times of weekly drinking,bilateral onset,≤6 months of disease course,ARCO phaseⅢin stage of ARCO and TCM type of CHANNELS STAGNATION.