认知行为疗法对梅毒ⅠⅡ期患者精神障碍的影响

Effect of cognitive behavior therapy on mental disorders in patients with primaryor secondary syphilis

目的观察认知行为疗法对梅毒Ⅰ、Ⅱ期患者精神障碍的影响。方法以2016年1月至2017年3月于张家口市第一医院皮肤性病科门诊就诊的64例梅毒Ⅰ、Ⅱ期患者为研究对象,其中,Ⅰ期患者36例,Ⅱ期患者28例。根据随机数字表法分为观察组和对照组,每组各32例。对照组给予常规治疗和护理,观察组在给予常规治疗和护理的基础上加用认知行为治疗。比较两组患者治疗前和治疗后4周焦虑自评量表(SAS)、抑郁自评量表(SDS)和Barthel指数量表测评分值。结果治疗前,观察组和对照组SAS评分分别为(54.05±4.80)分和(52.94±5.05)分,SDS评分分别为(54.16±4.82)分和(55.43±4.13)分,两组差异无统计学意义(P>0.05)。观察组治疗4周后,SAS、SDS评分分别为(49.25±3.16)分、(48.49±3.23)分,均低于对照组的(51.90±3.07)分和(51.77±3.67)分,差异有统计学意义(P<0.05);观察组Barthel指数优于对照组(Z=2.466,P=0.014),且其日常生活能力高于治疗前(Z=2.611,P=0.009)。结论认知行为疗法可以改善梅毒Ⅰ、Ⅱ期患者的精神障碍,同时还可以提高其日常生活能力。

Objective To observe the curative effect of cognitive behavior therapy on mental disorders in those patients with primary or secondary syphilis.Methods From Jan 2016 to Mar 2017,64 cases of out patients with primary or secondary syphilis treated in our hospital were enrolled as the study objectives,including 36 cases with primary syphilis and 28 cases with secondary syphilis.All patients were divided into the study group and the control group by means of random number table,32 cases in each group.Besides routine treatment and care given to the control group,patients in the study group received additional cognitive behavior therapy.Scores of self-rating anxiety scale(SAS),self-rating depression scale(SDS)and Barthel index scale before treatment and 4 weeks after treatment between the two groups were compared.Results Before treatment,the SAS scores of the study and control groups were(54.05±4.80)and(52.94±5.05),respectively,and the SDS scores of them were(54.16±4.82)and(55.43±4.13),respectively,with no significant difference between the two groups(P>0.05).After 4 weeks of cognitive behavior therapy,the scores of SAS(49.25±3.16)and SDS(48.49±3.23)in the study group were significantly lower than those in the control group[(51.90±3.07),(51.77±3.67);P<0.05].In the study group,the Barthel index after treatment was better than that in the control group(Z=2.466;P=0.014),and its daily living ability after treatment was higher than that before treatment(Z=2.611;P=0.009).Conclusion Application of cognitive behavior therapy can not only relievethe mental disorders of patients with primary or secondary syphilis,but also improve their daily living abilities.