性生活、前列腺疾病及HPV感染情况与前列腺癌的关系研究

Study on the relationship between the sexual life,prostate disease,HPV infection situation and prostatic carcinoma

目的:研究与观察性生活、前列腺疾病及HPV感染情况与前列腺癌的关系。方法:选取2015年1月至2016年12月期间本院收治的60例前列腺癌患者为观察组,同时期的60名健康体检者为对照组。将两组的性生活评估指标、前列腺疾病史及HPV感染情况进行比较,同时以多因素Logistic回归分析处理性生活评估指标、前列腺疾病史及HPV感染情况与前列腺癌的关系。结果:观察组的初次遗精年龄较小、性生活年龄较小、手淫、30岁之前性生活频率较高、前列腺炎史、前列腺增生病史、其他前列腺疾病史、HPV16、HPV18及HPV33感染者比例高于对照组,P<0.05,差异有统计学意义,且多因素Logistic回归分析显示,上述因素均与前列腺癌有密切的关系。结论:性生活、前列腺疾病及HPV感染情况均对前列腺癌的发生有影响,应针对上述因素进行防控措施的制定。

Objectives:To study and observe the relationship between the sexual life,prostate disease,HPV infection situation and prostatic carcinoma.Methods:60 patients with prostatic carcinoma in our hospital from January 2015 to December 2016 were selected as the observation group,and 60 healthy persons at the same ages were selected as the control group.The sexual life evaluation results,prostate disease history and HPV infection situation of the two groups were compared,and the relationship between the sexual life,prostate disease,HPV infection situation and prostatic carcinoma were analyzed by the multivariate Logistic regression analysis.Results:The rates of observation group with smaller age of first emission,smaller age of sexual life,manustupration,high frequency of sexual life before 30 years old,prostatitis history,hyperplasia of prostate history,other prostate history,HPV 16 infection,HPV18 infection and HPV33 infection were higher than those of control group,with statistically significant differences(P<0.05).The multivariate Logistic regression analysis showed that those factors all had close relationship with the prostatic carcinoma.Conclusion:The sexual life,prostate disease and HPV infection situation are all risk factors of prostatic carcinoma,and prevention and control measures should be taken according to those factors.