人乳头瘤病毒及行为危险因素与子宫颈癌的临床关系研究

Study on the relationship between human papillomavirus and behavioral risk factors and cervical cancer

目的:探讨人乳头瘤病毒及行为危险因素及与子宫颈癌的临床关系。方法:取2015年1月至2016年12月医院收治的宫颈癌40例作为研究对象,设为观察组;取同期入院健康体检者40例,设为对照组。入院后完善相关检查,采用医院自拟问卷调查表对两组基本资料人乳头瘤病毒感染情况、行为因素进行单因素和多因素Logistic回归分析。结果:单因素结果显示,子宫颈癌发生率与性生活过早、性保健缺乏、吸烟等差异无统计学意义(P>0.05);子宫颈癌发生率与人乳头瘤病毒感染、行为因素中多个性伴侣、免疫力低下、口服避孕药等关系密切(P<0.05)。Logistic回归分析显示子宫颈癌发生率与人乳头瘤病毒感染、行为因素中多个性伴侣、免疫力低下、口服避孕药等关系密切(P<0.05)。结论:子宫颈癌发生、发展诱因较多,包括人乳头瘤病毒感染、行为因素等,故应加强女性子宫颈癌筛查,以降低子宫颈癌发生率。

Objectives:To investigate the clinical relationship between human papillomavirus and behavioral risk factors and cervical cancer.Methods:From January 2015 to December 2016,40 patients with cervical cancer were treated as the observation group,and 40 healthy persons for physical examination were admitted to the control group.The human papillomavirus infection and behavioral factors in the two groups were analyzed and compared by univariate and multivariate logistic regression analysis.Results:The incidence of cervical cancer was not significantly correlated with early sexual life,lack of sex healthcare and smoking(P>0.05).The incidence of cervical cancer was significantly correlated with human papillomavirus infection,behavioral factors in multiple sexual partners,low immunity and oral contraception(P<0.05).Conclusion:The incidence of cervical cancer is correlated with human papillomavirus infection and behavioral factors,and the female cervical cancer screening should be strengthened to reduce the incidence of cervical cancer