合并小剂量氨磺必利对长期住院精神分裂症患者阴性症状疗效的研究

Combined with Small dose of Amisulpride on the Effect of Schizophrenia Negative Symptoms in Patients with Long-term Hospitalization

目的:研究合并小剂量氨磺必利对长期住院精神分裂症患者阴性症状的疗效。方法:抽取过去一段时期内长期在我院住院接受治疗的精神分裂症患者40例作为研究对象,对其在原有用药基础上增加小剂量氨磺必利进行治疗。对比患者治疗前后PANSS量表和SANS量表评分的改善幅度、临床治疗效果。结果:患者治疗前与治疗后比较,PANSS量表和SANS量表评分差异显著,组间各对应数据比较差异显著(P<0.05)。精神分裂症治疗总有效率为90.0%;仅有1例药物原因导致的不良反应出现。结论:小剂量氨磺必利对长期住院精神分裂症患者阴性症状有一定疗效,能更好地治疗患者阴性症状,降低精神分裂症致残率,使患者能更好地回归社会。

Objective:To study the efficacy of combined with low-dose sulforubicin in patients with long-term hospitalized schizophrenia.Methods:Forty patients with schizophrenia who were hospitalized in our hospital for a long period of time were selected as the research object,and the patients were treated with low-dose sulforamis on the basis of the original drug.The improvement rate of PANSS scale and SANS scale before and after treatment was compared with the clinical treatment.Results:Compared with the control group,the PANSS scale and the SANS scale were significantly different between the two groups(P<0.05).The total effective rate of schizophrenia treatment was 90.0%;only 1 case Drugs caused by adverse reactions.Conclusion:By studying the effect of low dose of sulfadiazole on negative symptoms of long-term hospitalized schizophrenia patients,it is better to treat patients with negative symptoms and reduce the morbidity of schizophrenia,so that patients can return to society better.