硫酸镁联合硝苯地平治疗妊高症的临床效果

Clinical Effect of Magnesium Sulfate Combined with Nifedipine in the Treatment of Pregnancy Induced Hypertension

目的:探讨硫酸镁联合硝苯地平治疗妊高症的临床效果。方法:抽取我院妇产科2015年1月—2017年10月间收治的100例妊高症患者为研究对象,随机分为对照组与观察组。对照组用硫酸镁治疗,观察组在此基础上加用硝苯地平,比较两组临床效果。结果:对照组治疗总有效率为80.0%,观察组治疗总有效率为96.0%,差异有统计学意义(P<0.05);两组治疗前脐动脉阻力指数(RI)、红细胞比容(HCT)和血粘度差异不明显,无统计学意义(P>0.05);治疗后,观察组对应指标明显低于对照组,差异存在统计学意义(P<0.05);比较两组不良反应发生率,差异不明显(P>0.05)。结论:硫酸镁联合硝苯地平治疗妊高症效果明显,即可改善临床指标,又能减少不良反应,值得推广应用。

Objective:To investigate the clinical effect of Magnesium Sulfate combined with nifedipine on pregnancy induced hypertension.Methods:100 cases of PIH patients treated in our hospital from January 2015 to October 2017 were selected and divided into the control group and the observation group.The control group was treated with Magnesium Sulfate,and the observation group was added nifedipine on the basis of this,and the clinical effect of the two groups was compared.Results:The treatment group total effective rate was 80%,the total efficiency of the observation group was 96%,the difference was statistically significant(P<0.05);the two groups before treatment of umbilical artery resistance index(RI),hematocrit(HCT)and blood viscosity showed no significant difference(P>0.05).After treatment,the observation group corresponding index was significantly lower than the control group(P<0.05);the incidence of adverse reactions of two groups showed no significant difference(P>0.05).Conclusion:The effect of Magnesium Sulfate combined with nifedipine in the treatment of pregnancy induced hypertension is obvious.It can improve the clinical index and reduce the adverse reaction.Thus,it is worth popularizing.