中药方洗浴对新生儿黄疸血清转铁蛋白与C反应蛋白的影响

Effect of Chinese herbal bath on serum transferrin and C-reactive protein in neonatal jaundice

目的:探究中药方洗浴对新生儿黄疸血清转铁蛋白与C反应蛋白的影响。方法:选取新生儿黄疸患儿83例。按照随机数表法,随机分为对照组与治疗组,对照组42例,治疗组41例。对照组行蓝光照射治疗,治疗组在对照组基础上给予中药方洗浴。观察两组患儿CRP、TRF、TBIL、TBA、ALP、AST、ALT水平、总有效率及不良反应总发生率。结果:对照组治疗后C反应蛋白(CRP)水平(16.75±1.59)mg/L明显高于治疗组(10.37±1.13)mg/L,治疗组治疗后转铁蛋白(TRF)水平(1.72±0.24)g/L明显高于对照组(1.53±0.23)g/L,差异有统计学意义(P<0.05)。对照组治疗后TBIL、TBA水平(105.41±21.46)μmol/L、(28.31±4.05)μmol/L明显高于治疗组(58.35±8.29)mg/L、(22.81±3.28)μmol/L,对照组治疗后ALP、AST、ALT水平(218.21±32.40)mmol/L、(49.87±6.92)mmol/L、(158.11±21.67)mmol/L明显高于治疗组(171.38±28.64)mmol/L、(44.96±6.23)mmol/L、(103.26±15.01)mmol/L,差异有统计学意义(P<0.05)。治疗组总有效率95.12%明显高于对照组76.19%,治疗组不良反应总发生率4.88%明显低于对照组16.67%,差异有统计学意义(P<0.05)。结论:中药方洗浴能够升高转铁蛋白水平,降低C反应蛋白水平,提高黄疸治疗总有效率,降低不良反应总发生率。

Objective:To explore the effect of self-made Chinese herbal medicine bath on serum transferrin and C-reactive protein in neonatal jaundice.Methods:Eighty-three children with neonatal jaundice were selected.According to random number table method,were randomly divided into control group and treatment group,control group 42 cases,treatment group 41 cases.The control group was treated with blue light irradiation,and the treatment group was given a self-made Chinese herbal bath on the basis of the control group.The levels of CRP,TRF,TBIL,TBA,ALP,AST and ALT,the total effective rate and the total incidence of adverse reactions in both groups were observed.Results:The level of CRP in the control group(16.75±1.59)mg/L was significantly higher than that in the treatment group(10.37±1.13)mg/L,and the level of TRF in the treatment group(1.72±0.24)g/L was significantly higher than that of the control group(1.53±0.23)g/L,the difference was statistically significant(P<0.05).The levels of TBIL and TBA in the control group(105.41±21.46)μmol/L,(28.31±4.05)μmol/L were significantly higher than those in the treatment group(58.35±8.29,22.81±3.28)mg/L The levels of ALP,AST,ALT in the control group were significantly higher than those in the control group(218.21±32.40 mmol/L,(49.87±6.92)mmol/L,(158.11±21.67)mmol/L.The difference was statistically significant(P<0.05)in the treatment group(171.38±28.64)mmol/L,(44.96±6.23)mmol/L,(103.26±15.01)mmol/L.The total effective rate was 95.12%in the treatment group and 76.19%in the control group.The total incidence of adverse reactions in the treatment group was 4.88%,which was significantly lower than that in the control group(16.67%,P<0.05).Conclusion:Self-Chinese medicine bathing can increase transferrin levels,reduce C-reactive protein levels,improve the total efficiency of jaundice treatment,reduce the overall incidence of adverse reactions.