抗生素与安宫黄体酮联合治疗子宫内膜炎的临床效果

Clinical effect of antibiotics combined with medroxy progesterone in the treatment of endometritis

目的探讨抗生素与安宫黄体酮联合治疗子宫内膜炎的临床效果。方法选取在我院接受治疗的60例子宫内膜炎患者,随机分为试验组及对照组,每组30例,对照组患者给予单纯抗生素治疗,试验组患者给予抗生素与安宫黄体酮联合治疗。对两组患者的治疗效果进行比较。结果试验组患者的总有效率为96.7%,明显高于对照组的80.0%(P<0.05)。治疗后,两组患者的MMP-9、IL-2、IL-4及IL-10水平均明显优于治疗前,且试验组明显优于对照组(P<0.05)。试验组患者子宫内膜厚度及子宫状态恢复时间明显优于对照组(P<0.05)。试验组患者月经恢复正常率明显高于对照组,阴道不规则出血率明显低于对照组(P<0.05)。结论抗生素与安宫黄体酮联合治疗子宫内膜炎临床效果显著,安全性较高,可有效促进患者子宫状态恢复,改善月经情况,值得临床推广应用。

Objective To investigate the clinical effect of antibiotics combined with medroxy progesterone in the treatment of endometritis.Methods Sixty endometritis patients admitted in our hospital were selected as the study objects.All the patients were randomly divided into experimental group and control group,with 30 cases in each group.The control group received antibiotics treatment,and the experimental group accepted antibiotics combined with medroxy progesterone.The clinical effects of the two groups were compared.Results The total effective rate of the experimental group was 96.7%,which was higher than 80.0%of the control group(P<0.05).After treatment,the levels of MMP-9,IL-2,IL-4 and IL-10 of the two groups were better than those before treatment,and those of the observation group were better than the control group(P<0.05).The endometrium thickness and the recovery time of the uterus in the experimental group were obviously superior to those of the control group(P<0.05).The rate of normal menstruation in the experimental group was significantly higher than that in the control group,and the irregular vaginal bleeding rate was significantly lower than that of the control group(P<0.05).Conclusion Antibiotics combined with medroxy progesterone in the treatment of endometritis has remarkable clinical effect and high safety,it can effectively promote the recovery of the state of the uterus and improve the situation of menstruation,which is worthy of clinical application.