盐酸氨溴索雾化吸入辅助治疗新生儿肺炎的疗效观察

Clinical effect of aerosol inhalation of ambrosial hydro chloride in the treatment of neonatal pneumonia

目的探讨盐酸氨溴索雾化吸入辅助治疗新生儿肺炎的临床效果。方法选取我院2015年1月至2016年1月收治的120例新生儿肺炎为此次研究对象,随机将患儿分为对照组和研究组,每组60例患儿。对照组患儿采用常规盐酸氨溴索静脉输液治疗,研究组患儿采用盐酸氨溴索电动压缩雾化吸入治疗。观察比较两组患儿的各项临床指标和治疗效果。结果研究组患儿血气分析恢复正常时间为(2.95±1.43)d,呼吸频率恢复正常时间为(3.47±1.18)d、肺部啰音消失时间为(6.13±2.27)d、住院时间为(9.48±2.85)d,均分别明显短于对照组患儿的(5.28±1.67)d、(6.28±2.36)d、(9.21±3.23)d及(11.13±4.48)d,差异均具有统计学意义(P<0.05)。研究组患儿的临床治疗显效率明显高于对照组,差异有统计学意义(P<0.05)。结论新生儿肺炎采用盐酸氨溴索雾化吸入治疗,不仅能够改善患儿的临床症状,还可以缩短治疗时间,提高临床治疗效果,具有良好的应用和推广价值。

Objective To study the clinical effect of aerosol inhalation of ambrosial hydro chloride in the treatment of neonatal pneumonia.Methods From January 2015 to January 2016,120 cases of neonatal pneumonia treated in our hospi原tal were selected as the research objects,the neonatus were randomly divided into control group and research group,with 60 cases in each group.The control group was treated with conventional ambroxol hydrochloride intravenous infusion,while the research group received electric compression aerosol inhalation of ambrosial hydro chloride.The clinical indicators and treatment effects were compared in the two groups.Results The blood gas analysis returning to normal time,respiration rate returning to normal time,pulmonary rales disappearance time and hospitalization time in the research group were(3.47±1.18)d,(6.13±2.27)d,(9.48±2.85)d,(5.28±1.67)d,which were significantly shorter than(2.95±1.43)d,(6.28±2.36)d,(9.21±3.23)d and(11.13±4.48)d of the control group,the differences were statistically significant(P<0.05).The effective rate of clinical treatment in study group was significantly higher than that of the control group,the difference was statistically significant(P<0.05).Conclusion Aerosol inhalation of ambrosial hydro chloride in the treatment of neonatal pneumonia has significant effect,which not only can improve the clinical symptoms of children,but also can shorten the treatment time and improve the clinical treatment effect,it has good application and promotion value