尼莫地平对高血压脑出血患者的脑血肿、脑水肿的疗效分析

Effect of nimodipine on cerebral hematoma and brain edema in patients with hypertensive cerebral hemorrhage

目的探讨尼莫地平对高血压脑出血患者的脑血肿、脑水肿的疗效。方法将2012年3月至2016年3月我院收治的高血压脑出血患者200例随机分成对照组与观察组,每组100例。对照组采用内科常规治疗,观察组在此基础上采用尼莫地平治疗。比较两组患者的治疗总有效率、治疗前、后的ESS评分及脑水肿与脑血肿量。结果治疗后,两组患者的ESS评分均降低,且观察组低于对照组(P<0.05);观察组患者的治疗总有效率显著高于对照组(P<0.05)。治疗后,两组患者的脑水肿与脑血肿量均降低,且观察组低于对照组(P<0.05)。结论高血压脑出血患者在常规治疗的基础上应用尼莫地平,不仅能有效减少患者的脑血肿与脑水肿量,而且治疗效果显著,值得在临床上推广应用。

Objective To investigate the effect of nimodipine on cerebral hematoma and cerebral edema in patients with hypertensive intracerebral hemorrhage.Methods From March 2012 to March 2016,200 patients with hypertensive intracerebral hemorrhage admitted to our hospital were randomly divided into control group and observation group,with 100 cases in each group.The control group was treated with routine treatment,and the observation group was treated with nimodipine on the basis of the control group.The total effective rates,ESS scores and brain edema and cerebral hematoma volumes before and after treatment of the two groups were compared.Results After treatment,ESS scores of both groups decreased,and that of the observation group was lower than the control group(P<0.05).The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,cerebral hematoma and brain edema volumes of both groups decreased,and those of the observation group were lower than the control group(P<0.05).Conclusion Nimodipine on the basis of the routine treatment in patients with hypertensive cerebral hemorrhage not only can effectively reduce the cerebral hematoma and brain edema volumes,but also has significant treatment effect,which is worthy of clinical application.