曲安奈德联合地塞米松上睑板内注射治疗小儿春季角结膜炎（英文）

Efficacy of supratarsal injection of triamcinolone acetonide and dexamethasone sodium phosphate in treating paediatric vernal keratoconjunctivitis in suburban Malaysia

马来西亚理科大学5a来使用曲安奈德混悬型注射液与地塞米松磷酸钠治疗小儿春季角结膜炎(VKC)的疗效研究。10例联合注射治疗患者注射1mo后症状有所改善。其中4例患者主要并发症为眼压增高。6mo内有4例患者复发。研究发现上睑板联合注射两种皮质类固醇治疗春季角膜炎的临床效果与文献报道使用单一皮质类固醇剂非常相似。然而,该治疗方法眼压升高的风险较大。

This study aims to describe the treatment efficacy of supratarsal injection of triamcinolone acetonide and dexamethasone sodium phosphate for paediatric vernal keratoconjuctivitis(VKC)over a 5-year-period in Hospital Universiti Sains Malaysia.Totally 10 patients were treated with this combination injection had clinical improvement by 1mo post injection.The main complication was increased intraocular pressure(4 patients).Four patients had recurrences within 6mo.We concluded that the clinical response to supratarsal combination corticosteroids in VKC is fairly similar to that reported in the literature using a single corticosteroid agent.However,the risk of increased intraocular pressure is higher.