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产妇B群链球菌筛查及青霉素敏感度分析 被引量:4

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摘要 目的分析产妇围产期B群链球菌(GBS)筛查结果及青霉素敏感度,为临床预防感染及合理用药提供指导。方法回顾性分析2014年4月至2017年4月于我院产科行产前检查的围产期孕妇临床资料,取其阴道拭子标本和直肠拭子标本送病理检查,进行GBS分离培养及鉴定与药敏试验,筛查GBS感染,并分析常用抗菌药物的药敏试验结果。结果共送检500例标本,检出GBS菌株45株,总检出率9.00%,其中不同标本类型、不同年龄段及不同季节间GBS检出率比较差异无统计学意义(P>0.05),但居住在城市的产妇GBS检出率(18.03%)低于居住在农村的产妇(7.74%),差异具有统计学意义(P<0.05);药敏试验结果显示,GBS对多种抗菌药物均具有较高抗菌活性,对青霉素、万古霉素、头孢噻肟、美洛培南、厄他培南、利奈唑胺100.0%敏感,对头孢唑啉、苯唑西林、替考拉宁耐药率均<10.0%,对左氧氟沙星、莫西沙星耐药率均>45.0%,对克林霉素、红霉素耐药率均>65.0%。结论产妇GBS带菌率与标本类型、患者年龄及季节差异无显著相关性,需将居住在农村的产妇作为GBS重点筛查对象,并根据药敏试验结果指导临床用药,青霉素可作为首选药物,改善产妇预后。
出处 《实用医技杂志》 2018年第3期282-284,共3页 Journal of Practical Medical Techniques
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