摘要
WRKY转录调控因子是植物中最大的转录调控因子家族之一,包含1或2个大约由60个氨基酸残基组成的高度保守的WRKY结构域。WRKY结构域的N端有严格保守的WRKYGQK氨基酸序列,其C端有锌指结构模型Cys(2)-His(2)或Cys(2)-His Cys。WRKY转录调控因子与靶基因启动子区域的DNA序列(T)TGAC(C/T)(W盒)特异性结合,调节目的基因的表达,在调控植物生长发育、物质代谢、抗病耐逆及氧化衰老过程中起重要作用。我们就有关水稻WRKY转录调控因子的结构分类及其生物学功能的研究进展做简要综述。
WRKY transcription factors are one of the largest families of transcriptional regulators in plants which contain either one or two 60-amino-acid regions that contain the amino-acid sequence WRKYGQK at the N-terminus and the zinc-finger-like motifs Cys(2)-His(2)or Cys(2)-HisCys at the C-terminus.WRKY transcription factors bind specifically to the(T)TGAC(C/T)nucleotides known as W-box in the promoter of their target genes to regulate gene expresssion.WRKY transcription factors play pivotal roles in the regulation of plant development,metabolism,stress resistance and senescene.In this article we reviewed the current research progress of the structure and biological function of WRKY transcription factors in rice.
作者
郑超
郑二松
王栩鸣
李冬月
杨勇
余初浪
周洁
严成其
陈剑平
ZHENG Chao;ZHENG Er-Song;WANG Xu-Ming;LI Dong-Yue;YANG Yong;YU Chu-Lang;ZHOU Jie;YAN Cheng-Qi;CHEN Jian-Ping(College of Chemistry and Life Sciences,Zhejiang Normal University,Jinhua 321004,China;State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control,MOA Key Laboratory for Plant Protection and Biotechnology,Zhejiang Provincial Key Laboratory of Virology,Institute of Virology and Biotechnology,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China)
出处
《生物技术通讯》
CAS
2018年第2期286-294,共9页
Letters in Biotechnology
基金
浙江省自然科学基金(Y16C140005,NB2016C11017)
国家重点研发计划(2016YFD0100601-15)