乳腺导管原位癌超声造影特征的临床研究

Features of breast ductal carcinoma in situ on contrast-enhanced ultrasound

目的:回顾性探讨单纯乳腺导管原位癌(ductal carcinoma in situ,DCIS)及DCIS伴浸润性乳腺癌的超声造影(contrast-enhanced ultrasound,CEUS)表现特征。方法:对261例住院患者进行术前CEUS检查,根据术后病理结果,选取14例单纯DCIS(A组)和29例DCIS伴浸润性乳腺癌[原位癌成分≥20%者14例(B组)和原位癌成分<20%者15例(C组)],并对患者进行CEUS分析。结果:单纯DCIS多表现为边缘到中央整体中高强度灌注,部分周边可见血管样灌注,其中部分可呈环形血管样灌注。A组比B组曲线下面积大,上升斜率高,差异有统计学意义。结论:单纯DCIS及DCIS伴浸润性乳腺癌的CEUS具有一定的特征性表现。

Objective:To retrospectively study the performance of pure breast ductal carcinoma in situ(DCIS)and invasive ductal carcinoma accompanied by DCIS on contrast-enhanced ultrasound(CEUS).Methods:A total of 261 patients received pre-surgical CEUS,and 14 pure DCIS(group A)and 29 mixed patients were selected.The 29 mixed patients were further divided into two groups according to the DCIS component proportion:proportion≥20%(14 cases,group B),proportion<20%(15 cases,group C).Then CEUS analysis was conducted.Results:The pure DCIS was characterized by the edge to central perfusion with high intensity,and vascular perfusion in some peripheral areas with ring enhancement sometimes.Group A had a larger area under the curve and a steeper ascending slope compared with group B.Conclusion:The CEUS manifestations of pure DCIS and invasive ductal carcinoma accompanied by DCIS are some what different about the characteristics.