氨氯地平单药及与阿托伐他汀联合治疗高血压合并糖尿病的临床疗效比较

Comparison of the clinical efficacy of amlodipine and atorvastatin in the treatment of hypertension and diabetes

目的:探讨氨氯地平单药及与阿托伐他汀联合治疗高血压合并糖尿病的疗效。方法:收治高血压合并糖尿病患者90例,分为参照组和联合组,各45例。参照组使用氨氯地平治疗,联合组在参照组基础上联合阿托伐他汀治疗。结果:联合组总体疗效显著高于参照组(P<0.05);治疗后,联合组舒张压、收缩压以及血脂改善均明显佳于参照组(P<0.05)。结论:氨氯地平联合阿托伐他汀治疗高血压合并糖尿病患者比单独应用氨氯地平效果理想,两者联用能更好地控制血压,改善血脂水平,药效稳定且不增加不良反应。

Objective:To investigate the effect of amlodipine and atorvastatin in the treatment of hypertension and diabetes.Methods:90 patients with hypertension and diabetes were selected.They were divided into the reference group and the combined group with 45 cases in each group.The reference group was treated with amlodipine,and the combined group was treated with atorvastatin on the basis of the reference group.Results:The overall efficacy of the combined group was significantly higher than that of the reference group(P<0.05).After the treatment,the improvement of diastolic blood pressure,systolic blood pressure and blood lipid status in the combined group were significantly better than those of the reference group(P<0.05).Conclusion:Amlodipine combined with atorvastatin in the treatment of hypertension and diabetic patients is better than amlodipine alone.The combination of them can better control the blood pressure of patients and improve their blood lipid level,and the effect is stable without increasing adverse reactions.