经皮肾镜取石术与输尿管镜碎石术治疗嵌顿性输尿管上段结石的临床有效性分析

Clinical efficacy of percutaneous nephrolithotomy and ureteroscopic lithotripsy for the treatment of incarcerated upper ureteral calculi

目的:探讨经皮肾镜取石术以及输尿管镜碎石术治疗嵌顿性输尿管上段结石的效果。方法:收治嵌顿性输尿管上段结石患者168例,分为对照组和研究组,各84例。对照组给予经尿道输尿管镜碎石术治疗,研究组给予经皮肾镜取石术治疗。结果:研究组结石清除率高于对照组(P<0.05)。研究组手术时间以及住院时间均显著少于对照组(P<0.05);研究组术后并发症发生率低于对照组(P<0.05);两组术后NGAL水平均显著性高于术前,研究组低于对照组(P<0.05)。结论:对比经尿道输尿管镜碎石术,针对嵌顿性输尿管上段结石患者应用经皮肾镜取石术治疗,其结石清除率更高,并发症发生率更低,住院时间更短,对肾功能影响更小。

Objective:To investigate the effect of percutaneous nephrolithotomy and ureteroscopic lithotripsy for the treatment of incarcerated upper ureteral calculi.Methods:168 cases of incarcerated upper ureteral calculi were selected.They were divided into the control group and the study group with 84 cases in each group.The control group was treated with transurethral ureteroscopic lithotripsy,and the study group was treated with percutaneous nephrolithotomy.Results:Stone clearance rate of study group was higher than the control group(P<0.05);the operation time and hospitalization time were significantly less than the control group(P<0.05);the study group of patients with postoperative complications was lower than the control group(P<0.05);the level of NGAL in the two groups was significantly higher than that before the operation,and the study group was lower than the control group(P<0.05).Conclusion:Compared with transurethral ureteroscopic lithotripsy,percutaneous lithotripsy for patients with impacted upper ureteral calculi has higher stone clearance rate,lower incidence of complications,shorter hospitalization time and less impact on renal function.