胰腺实性假乳头状瘤的临床诊治分析

Diagnosis and treatment of solid-pseudopapillary tumor of pancreas

目的:探讨胰腺实性假乳头状瘤的临床特征、影像学表现、病理特征、治疗与预后情况。方法:回顾性分析2007年3月—2017年3月收治的49例胰腺实性假乳头状瘤患者的临床资料。结果:49例胰腺实性假乳头状瘤患者中男性11例,女性38例,男女比例为1:3.5,患者平均年龄为(31.4±13.2)岁。患者多无特异性临床表现。术前影像学检查对于判定肿瘤的位置、性质方面有重要的意义,但肿瘤的性质仍待术后病理证实。49例患者均行手术治疗,47例行根治性切除。21例患者术后出现并发症,胰瘘是患者术后主要严重并发症。结论:胰腺实性假乳头状瘤好发于年轻女性,无特异性临床表现,影像学检查对于SPT的术前诊断及鉴别诊断有着重要的意义。绝大多数患者可得到根治性切除,预后较好。

Objective:To explore the clinical characteristics,imaging features,biological characteristics,treatment and prognosis of solid-pseudopapillary tumor of pancreas(SPT).Methods:Retrospectively reviewed and analyzed clinical and pathological data of 49 cases of SPT from 2007.3 to 2017.3.Results:Among 49 SPT patients,11 males and 38 females,male-to-female ratio was 1:3.5,with a mean age of(31.4±13.2)years old.There was nonspecific symptoms among patients.Preoperative imaging help to determine the location of the tumor and make the correct diagnosis,but the nature of the tumor remains to be pathologically confirmed.All of patients renceived surgery,47 patients were treated by radical tumor resection,21 patients presented with postoperative complications,the most common complication was pancreatic fistula.Conclusion:Solid pseudopapillary tumor(SPT)is a rare low grade malignancy more frequent in young women with non-specific clinical characteristics.Preoperative imaging has important significance in the preoperative and differential diagnosis.Most of patients can receive radical resection and have good prognosis.