泻腑贴方穴位贴敷对慢性阻塞性肺疾病急性加重期的临床研究

Clinical Study of Effect of Acupoint Application of Purgation and Sticking Therapy on Chromc Obstructive Pulmonary Disease with Acute Exacerbation

目的:探讨泻腑贴方穴位贴敷在治疗慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary diseases,AECOPD)中的临床效果。方法:选取2016年1月-2017年5月本院收治的AECOPD合并腑实证患者200例,按照随机数字表法将其分为对照组和治疗组,各100例。两组均接受西医规范化治疗和中医治疗,治疗组在此基础上给予泻腑贴方穴位贴敷治疗,两组均持续治疗10 d。比较两组治疗前后的临床症状、体征、COPD评估测试评分(COPD Assessment Test,CAT),比较两组治疗前后的肺功能和动脉血气分析,包括第一秒用力呼气量(forced expiratory volume in first second,FEV_1)、用力肺活量(forced vital capacity,FVC)、呼气流量峰值(peak expiratory flow,PEF)、氧分压(arterial partial pressure of oxygen,Pa O2)、二氧化碳分压(arterial partial pressure of carbon dioxide,PaCO_2)、pH值,以及比较两组住院时间。结果:治疗后,两组咳嗽、咯痰、胸闷、气短、腹胀、便秘评分均低于治疗前,且治疗组均低于对照组,比较差异均有统计学意义(P<0.05)。治疗后,两组肺功能和动脉血气分析指标均较治疗前改善,且治疗组FVC明显优于对照组,比较差异均有统计学意义(P<0.05);但两组FEV1、PEF、pH、PaCO_2、PaO_2比较,差异均无统计学意义(P>0.05)。治疗后,两组CAT评分均低于治疗前,且治疗组低于对照组,比较差异均有统计学意义(P<0.05)。治疗组住院时间短于对照组(P<0.05)。结论:泻腑贴方穴位贴敷可改善AECOPD合并腑实证患者的肠道功能和肺功能,提高其生活质量,是一种有效的中西医结合治疗手段。

Objective:To explore the clinical effect of the acupoint application of purgation and sticking therapy on chronic obstructive pulmonary disease with acute exacerbation(AECOPD).Method:A total of 200 patients with AECOPD combined with viscera sthenia syndrome in our hospital from January 2016 to May 2017 were selected,according to the random number table method,they were divided into control group and treatment group,100 cases in each group.They were received western medicine standardized treatment and traditional Chinese medicine treatment,on the basis of this,the treatment group was treated with the acupoint application of purgation and sticking therapy,they were treated with 10 d continuously.The clinical symptoms and signs,COPD Assessment Test(CAT)score in two groups before and after treatment were compared,the pulmonary function and arterial blood gas analysis index in two groups before and after treatment were compared,included forced expiratory volume in first second(FEV1),forced vital capacity(FVC),peak expiratory flow(PEF),arterial partial pressure of oxygen(PaO2),arterial partial pressure of carbon dioxide(PaCO2),pH,and the hospitalization time between the two groups was compared.Result:After treatment,the scores of cough,expectoration,chest tightness,shortness of breath,abdominal distension and constipation in treatment group were significantly lower than those of before treatment,and the treatment group were lower than those of control group,the differences were statistically significant(P<0.05).After treatment,the pulmonary function and arterial blood gas analysis were better than those of before treatment,and the FVC in treatment group was significantly better than that of control group,the differences were statistically significant(P<0.05),but the FEV1,PEF,pH,PaCO2 and PaO2 in two groups were compared,the differences were not statistically significant(P>0.05).After treatment,the CAT scores of two groups were lower than those of before treatment,and the treatment group was lower than that of control group,the differences were statistically significant(P<0.05).The the hospitalization time in treatment group was shorter than that of control group(P<0.05).Conclusion:Acupoint application of purgation and sticking therapy can improve the intestinal function and lung function in patients with AECOPD complicated with viscera sthenia syndrome,and improve the quality of life,is an effective method of combining traditional Chinese and Western medicine.