肺结核患者合并感染乙型肝炎病毒状况调查

A Survey on Hepatitis B Virus Infected among Pulmonary Tuberculosis Patients

目的了解肺结核患者的乙肝感染情况,为肺结核合并感染乙型肝炎防治提供参考。方法对襄阳市结核病防治院2014年1月至2015年3月确诊的肺结核患者进行HBV 5项(HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc)检测,检测结果用SAS9.2软件进行有关统计分析。结果共调查906名肺结核患者,男性和女性分别占72.74%、27.26%。所有患者的HBsAg阳性率16.23%,其中男性阳性率18.21%与女性10.93%差别有统计学意义,四组间HBsAg阳性率差异无统计学意义。所有调查者的HBV 5项检测阴性率41.50%,不同性别和年龄组之间HBV 5项检测阴性率差别无统计学意义。结论肺结核患者合并感染乙型肝炎病毒比例较高,将HBV检测纳入抗结核治疗前常规检测项目十分必要。

Objectives To understand the prevalence of hepatitis B virus among pulmonary tuberculosis patients and to provide reference for PTB and HBV co-infected disease control and prevention.Methods All of the patients diagnosed with pulmonary tuberculosis(PTB)during Jan 2014 to March 2015 in Xiangyang Hospital for Tuberculosis Prevention and Cure were detected 5 items of HBV infection indicators,5 items include HBsAg,anti-HBs,HBeAg,anti-HBe and anti-HBc.SAS9.2 software was utilized to analyze relevant data.Results 906 PTB patients were detected,72.74%were male and 27.26%female.16.23%patients were HBsAg positive,the rate of HBsAg positive of male patients was higher than female.41.50%objects were detected negative on 5 indicators,the differences between sex,5 groups had no statistical significance.Conclusions The PTB patients have high infection with hepatitis B virus,and the detection of HBV should be incorporated to routine testing projects before PTB treatment.