降钙素原对ICU发热患者血流感染的诊断及预测价值的临床研究

Clinical Study of Procalcitonin in the Diagnosis and Prediction of Bloodstream Infection in Patient with ICU Fever

目的:探讨降钙素原(Procalcitonin,PCT)对ICU发热患者血流感染的诊断及预测价值的临床研究。方法:选取2014年1月-2017年1月本院ICU收治的100例发热患者,根据其血流感染情况分为对照组(无血流感染,n=28)与观察组(有血流感染,n=72)。比较分析两组不同时间段血清PCT、CRP的检测结果及阳性检出率。结果:发热后12、24、36 h,观察组的PCT、CRP水平均明显高于对照组,差异均有统计学意义(P<0.05);观察组的阳性检出率明显高于对照组,差异有统计学意义(P<0.05)。结论:降钙素原对ICU发热患者血流感染的诊断有着良好的预测价值,可以作为诊断血流感染的预测指标,值得临床推广应用。

Objective:To investigate the clinical study of the diagnostic and predictive value of procalcitonin(PCT)in patients with bloodstream infection of ICU fever.Method:100 patients with fever from January 2014 to January 2017 were selected in ICU of our hospital,and the bloodstream infection were divided into the control group(no bloodstream infection,n=28)and the observation group(bloodstream infection,n=72).The results of serum PCT,CRP and positive rate in the two groups were compared and analyzed.Result:12,24 and 36 h after fever,the levels of PCT and CRP in the observation group were significantly higher than those in the control group,the differences were statistically significant(P<0.05).The positive rate of the observation group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Procalcitonin has a good predictive value in the diagnosis of bloodstream infection in patients with ICU fever,it can be used as a predictor of bloodstream infection and is worth popularizing in clinic.