间质性肺疾病中医证候与支气管肺泡灌洗液细胞学特征的研究

Study the Cytological Features of TCM Syndromes and Bronchoalveolar Lavage in Interstitial Lung Disease

目的:对间质性肺疾病(Interstitial Lung Disease,ILD)中医证候与支气管肺泡灌洗术(Bronchoalveolar lavage,BAL)显示的细胞学特征进行探讨。方法:选取本院在2016年3月-2017年2月收治的间质性肺疾病患者42例,全部患者均经中医证候诊断,再行支气管肺泡灌洗液检测,研究不同证候类型患者经BAL检验所显示细胞学特征。结果:在五种中医证候类型患者细胞学特征中均以巨噬细胞减少以及嗜中性粒细胞增多为临床表现,且该五种中医证候类型患者BAL细胞活性等指标比较,差异均有统计学意义(P<0.05)。结论:ILD五种中医证候类型都呈现了细胞学的特点,因此可以推测出不同证候疾病之间的细胞学病变存在着不同。

Objective:To study the cytological features of TCM syndromes and bronchoalveolar lavage(BAL)in interstitial lung disease(ILD).Method:A total of 42 ILD patients were selected in our hospital from March 2016 to February 2017,all patients were diagnosed by TCM symptoms,and underwent BAL,the cytological features by BAL were respectively researched in different types of TCM symptoms patients.Result:In the five types of TCM syndromes,the clinical manifestations were macrophage decrease and neutrophilic granulocyte increase,and cell viability by BAL in patients with indexes were compared in the 5 types TCM symptoms,the differences were statistically significant(P<0.05).Conclusion:The five types of TCM syndromes of ILD have the characteristics of cytology,so it can be inferred that there are different cytological lesions among different syndromes.