葡萄球菌性烫伤样皮肤综合征18例临床分析及治疗措施探讨

Clinical analysis and treatment measures for 18 patients with Staphylococcal scalded skin syndrome

目的探讨葡萄球菌性烫伤样皮肤综合征(SSSS)的临床特点及治疗策略。方法回顾性分析我院收治的18例SSSS患儿的临床表现和诊治过程。结果 18例葡萄球菌性烫伤样皮肤综合征多发生于4岁以下患儿。烫伤样皮损、口周放射状皲裂、疼痛、尼氏征阳性为主要临床表现。眼、口周常为首发皮损部位。早期合理使用抗生素疗效确切。结论掌握葡萄球菌性烫伤样皮肤综合征的临床特点有利于早期诊断,早期敏感抗生素治疗能有效缓解病情。

Objective To explore the clinical characteristics and the therapy strategy for the Staphylococcal scalded skin syndrome(SSSS). Methods The clinical manifestation and the course of diagnosis and treatment of 18 children with staphylococcal scalded skin syndrome cared in our hospital were retrospectively analyzed. Results Eighteen cases of staphylococcal scalded skin syndrome mostly occurred in children under 4 years old.The main clinical manifestations of staphylococcal scalded skin syndrome were scald skin lesion,perioral radial rhagades,pain and positive Nikolsky’s sign.The first sites that skin lesions usually occurred were eyes and mouths.The early rational use of antibiotics was effective for the disease. Conclusion To master the clinical features of staphylococcal scalded skin syndrome is beneficial to early diagnosis,and early sensitive antibiotic treatment can effectively alleviate the disease.