7例羊水栓塞患者临床特点分析及防治措施研究

Clinical characteristics analysis for 7 patients with amniotic fluid embolism and its prevention and treatment measures

目的探讨羊水栓塞患者临床特点及防治措施。方法选取2006年11月—2016年12月我院7例羊水栓塞患者,对其临床资料进行回顾性分析。结果本组7例羊水栓塞患者中,有5例经阴道试产中出现典型的紫绀、呼吸困难等症状,其中1例经阴道分娩,胎儿及产妇均死亡,4例改剖宫产后,1例产妇死亡,3例存活,新生儿出现不同程度窒息。另外2例剖宫产术后出现羊水栓塞者,1例产妇死亡,新生儿无窒息。结论羊水栓塞的主要临床特点包括DIC、凝血功能障碍和休克。早期采取积极有效的防治措施可以降低羊水栓塞的死亡率和提高抢救成功率。

Objective To explore the clinical characteristics of amniotic fluid embolism and its prevention and treatment measures. Methods From November 2006 to October 2016,clinical records of 7 patients with amniotic fluid embolism at our hospital were analyzed retrospectively. Results Five out of 7 patients with amniotic fluid embolism in this study group had typical cyanosis,dyspnea and other symptoms when they were undergoing vaginal delivery.Among 5 cases with vaginal delivery,one puerperant and her neonate all died.In 4 out of the 5 cases with vaginal delivery and altered to cesarean section later,1 puerperant died,3 puerperants survived,and neonates had varying degrees of asphyxia.In the other 2 out of the 7 patients who underwent cesarean section and had post-operative amniotic fluid embolism,1 puerperant died,no asphyxia occurred in the neonates. Conclusion Clinical features of amniotic fluid embolism mainly include DIC,coagulation dysfunction and shock.Early active and effective prevention and treatment measures can reduce the mortality of amniotic fluid embolism and improve the success rate of rescue.