国内外麻风病相关情况的研究进展

Research progress on leprosy in domestic and foreign countries

目的了解国内外关于麻风病地理分布、易感人群和分类方法的研究进展,为掌握麻风特性,控制并消除麻风危害提供科学依据。方法收集中国知网、万方数据库、Pub Med、EBSCO等数据库近几年与麻风相关的文献,结合中国疾病预防控制中心提供的国内麻风疫情数据进行比较。结果麻风病存在地域聚集性,人口较少的边缘化区域麻风患者数量较多。麻风的易感人群主要是青壮年男性,可能与男性青壮年人群社会活动广泛,接触传染源的机会更多有关。此外,麻风患病与遗传基因、细胞免疫有一定的关联。根据不同需求采取的分类方法主要有两型分类及Ridley-Jopling分类。结论麻风病是一个全球性健康问题,当前麻风患者的社会地位和生活质量在很多国家已经明显得到改善,但是,少数国家仍然疫情严重。未来全球还需共同努力,为最终实现全面消灭麻风的目标而奋斗。

Objective To understand the domestic and foreign research on the geographical distribution,susceptible populations and classification methods of 1eprosy,and grasp the characteristics of 1eprosy,so as to provide scientific basis for the control and elimination of leprosy.Methods Literature related with leprosy in recent years in CNKI,Wanfang data,PubMed,EBSCO and other databases was collected,and compared with the domestic leprosy data provided by the Chinese enter for Disease Control and Prevention.Results Leprosy had the feature of geographical aggregation Leprosy patients were concentrated in sparsely populated areas.The susceptible population of leprosy was mainly young and middle-aged males,w-hich might be associated with a wide range of social activities and had more exposure to the source of infection.In addition,leprosy was associated with genetic gene and cellular immunity.According to different needs,there were two types of classification,and Ridley-Jopling classification.Conclusion Leprosy is a global health problem.The current social status and quality of life of leprosy patients have been significantly improved in many countries,however,some countries were still seriously endemic.In the future,the world needs to work together to achieve the goal of the total elimination of leprosy.