拉萨市某三甲医院院内感染及多重耐药菌感染特点分析

Analysis of Nosocomial Infection and the Characteristics of Multi-resistance Organisms Infection in a Top Three Hospital of Lhasa

目的了解院内感染及多重耐药菌(MDROs)感染特点。方法对2016年10月~2017年6月入院所有患者进行前瞻性调查,调查医院感染及多重耐药菌感染情况。结果全院15674例患者中发生医院感染100例,医院感染率为0.64%;ICU感染率最高(13.90),明显高于其他科室(P<0.001);感染部位主要为呼吸道和手术部位;47株医院感染病原体以大肠埃希菌(23.40%)鲍曼不动杆菌(23.40%)和肺炎克雷伯菌(17.02%)为主。MDROs总的检出率为14.19%;以CR-AB和MRSA检出率最高,分别为71.43%和42.59%,而且这两种MDRO也是医院感染主要病原体。结论医院感染防控的重点为呼吸道感染,应重视抗菌药物合理使用,并贯彻多重耐药菌防控措施。

Objective:To understand the characteristics of nosocomial infection and multi-drug resistant organisms(MDROs)infection in a top three hospital of Lhasa.Methods:Prospective study was conducted on all patients admitted in our hospital from October 2016 to June 2017 for investigating nosocomial infection and MDROs infection.Results:The rate of nosocomial infection was 0.64%(100/15674),the infective rate(13.90)among ICU patients was higher than others(=526.04,P<0.001).The common nosocomial infection sites were respiratory tract surgical sites.The common pathogen of nosocomial infection were Escherichia coli(23.40%),Acinetobacter baumannii(23.40%),and Klebsiella pneumoniae(17.02%).The total detectable rate of MDROs was 14.19%.The detection rate of CR-AB(71.43%)and MRSA(42.59%)were the highest,and two of them became the pathogen of nosocomial infection.Conclusions:The respiratory infection is the main control and prevention target of nosocomial infection.It should be pay attention to the rational application of antibiotics to strengthen control measurements