PCI术对超高龄(≥80岁)心肌梗死患者心脏功能的远期疗效探讨

Long-term effectiveness of PCI on cardiac function in very elderly(≥80years) patients with myocardial infarction

目的探讨PCI术对年龄不低于80岁的超高龄心肌梗死患者进行治疗后患者心脏功能的远期疗效。方法选择2014年6月~2017年5月期间于我院接受治疗的200例超高龄心肌梗死患者,将其按随机的方式进行分组,对照组与试验组各100例。对照组的治疗方法为药物治疗,试验组的治疗方法为PCI治疗,治疗结束后对患者予以5~40个月的随访,将患者最后一次检查的LVEF指标、左心室质量指数等指标以及患者的死亡率进行比较。结果试验组患者的LVEDV、LVESV水平均显著低于对照组,而LVEF水平显著高于对照组,差异有统计学意义(P<0.05)。试验组的LVMI、LVD指标的水平均显著低于对照组,差异有统计学意义(P<0.05);而IVST、LVPWT水平与对照组相比无明显差异(P>0.05)。随访结果显示,试验组的死亡率为3.00%(3/100),对照组的死亡率为16.00%(16/100),差异有统计学意义(χ~2=9.83,P=0.00<0.05)。结论从远期来看,用PCI术对年龄不低于80岁的超高龄心肌梗死患者进行治疗后,患者的心脏功能得到较为明显的改善,且患者的死亡率较低,因而PCI术具有一定的推广意义。

Objective To investigate the changes of cardiac function after the treatment of PCI in very elderly patients who were aged no less than 80 years with myocardial infarction from the aspect of long-term effectiveness.Methods 200 very elderly patients with myocardial infarction in our hospital from June 2014 to May 2017 were selected and divided into control group and study group randomly with 100 patients in each group.Patients in control group were treated with medication and patients in study group were treated with PCI.Patients were followed up for 5 to 40 months after treatment.The levels of LVEF and left ventricular mass index and the mortality of patients were compared.Results The levels of LVEDV and LVESV in study group were significantly lower than those in control group while the level of LVEF in study group were significantly higher than that in control group(P<0.05).The levels of LVMI and LVD were significantly lower than those in control group(P<0.05).There were no statistical differences of the levels of IVST and LVPWT between study group and control group(P>0.05).Results of follow-up showed the mortality in study group was 3.00%(3/100)while that in control group was 16.00%(16/100)(χ2=9.83,P<0.05).Conclusion From long-term point of view,cardiac function is improved significantly and the mortality is low after the treatment of PCI in very elderly patients who are aged no less than 80 years with myocardial infarction.Thus,PCI is worth promotion.