彩色多普勒超声对糖尿病眼球后血流动力学改变评价中应用分析

Color Doppler ultrasound in evaluation of post-ocular hemodynamic changes in diabetic patients

目的 探讨彩色多普勒超声对糖尿病眼球后血流动力学改变评价中应用价值。方法 选择2016年1月至2017年5月在本院接受治疗的60例2型糖尿病眼病患者（120眼）为观察组，根据患者病情分为三组，其中糖尿病视网膜病变非增殖期（NPDR）组、糖尿病无视网膜病变（DNR）组、糖尿病视网膜病变增殖期（PDR）组，各20例（40眼），并选择同期在本院接受健康体检眼部正常的健康者60例（120眼）为对照组，均接受彩色多普勒超声检查。各组视网膜睫状后动脉（PCA）、视网膜中央动脉（CRA）、眼动脉（OA）的血流参数比较。结果 对照组CRA上EDV、PSV、RI分别为（5.69±1.23）cm/s、（12.57±2.20）cm/s、（0.56±0.07），DNR组上EDV、PSV、RI分别为（4.72±1.06）cm/s、（10.33±2.10）cm/s、（0.63±0.06），NPDR组上EDV、PSV、RI分别为（3.56±1.04）cm/s、（9.69±1.42）cm/s、（0.73±0.07），PDR组上EDV、PSV、RI分别为（2.56±0.89）cm/s、（7.26±1.34）cm/s、（0.79±0.08），差异有统计学意义（P＜0.05）；对照组PCA、OA上的舒张末期血流速度（EDV）、收缩期峰值流速（PSV）＞DNR组＞NPDR组＞PDR组，阻力指数（RI）＜DNR组＜NPDR组＜PDR组，差异有统计学意义（P＜0.05）。结论 彩色多普勒超声能动态监测视网膜血流状况，根据血流变化判断糖尿病视网膜病变程度，能为临床治疗提供参考依据。

Objective To evaluate the value of color Doppler ultrasound in the assessment of post-ocular hemodynamic changes in diabetic patients.Methods Sixty patients with type 2 diabetes mellitus(120 eyes)treated at our hospital from January,2016 to May,2017 were selected as an observation group and divided into a non-proliferative diabetic retinopathy(NPDR)group,a diabetic no-retinopathy(DNR)group,and a proliferative diabetic retinopathy(PDR)group according to the patients'conditions,20 cases(40 eyes)for each group.And 60 normal subjects(120 eyes)were set as a control group.All were examined with color Doppler ultrasound.The blood flow parameters of the posterior ciliary artery(PCA),the central retinal artery(CRA),and the ocular artery(OA)of each group were compared.Results The EDV,PSV,and RI of CRA were(5.69±1.23)cm/s,(12.57±2.20)cm/s,and(0.56±0.07)in the control group,were(4.72±1.06)cm/s,(10.33±2.10)cm/s,and(0.63±0.06)in the DNR group,were(3.56±1.04)cm/s,(9.69±1.42)cm/s,and(0.73±0.07)in the NPDR group,and were(2.56±0.89)cm/s,(7.26±1.34)cm/s,and(0.79±0.08)in the PDR group,with statistical differences(P<0.05)The enddiastolic velocity(EDV)and peak systolic velocity(PSV)were the highest in the control group,those in the DNR group came next,and those in the NPDR group,and those in the PDR group;the resistance index(RI)was the lowest in the control group,and second lowest in the DNR group,third in the NPDR group,and fourth in the PDR group;there were statistical differeces(P<0.05).Conclusions Color Doppler ultrasound can dynamically monitor the retinal blood flow status and determine the degree of diabetic retinopathy according to the changes of blood flow and can provide some references for clinical treatment.