摘要
目的研究黄花白及化学成分.方法黄花白及全草溶剂提取、硅胶柱层析和Sephadex LH-20柱层析进行分离纯化,波谱分析(核磁共振氢谱、碳谱、和质谱)确定结构.结果从该药用植物分离并鉴定了9个化合物,分别为:lusianthridin(1),1,2,7-trihydroxy-4-methoxy-9,10-dihydroxyphenanthrene(2),nudol(3),coelonin(4),batatasin Ⅲ(5),3,7-dihydroxy-2,4-dimethoxyphenanthrene(6),daucosterol(7),β-sitosterol(8),stigmasterol(9).结论化合物2,3,5为首次从本植物中分离得到.
Objective To study the chemical constituents from Bletilla Ochracea.Methods The compounds were extracted by 95%alcohol and isolated by column chromatography on silica gel and Sephadex LH-20.Their structures were identified by spectroscopic analysis(1H NMR and 13CNMR).Results Nine compouds were obtained and identified as lusianthridin(1),1,2,7-trihydroxy-4-methoxy-9,10-dihydroxyphenanthrene(2),nudol(3),coelonin(4),batatasin III(5),3,7-dihydroxy-2,4-dimethoxyphenanthrene(6),daucosterol(7),β-sitosterol(8),stigmasterol(9).Conclusion Compounds 2,3,5 were isolated fromthis plant for the first time.
作者
陶永生
李美红
董文茜
滕倩
黄荣
叶思蕾
沈居丽
叶吉云
李玉鹏
TAO Yong-sheng;LI Mei-hong;DONG Wen-xi;TENG Qian;HUANG Rong;YE Si-lei;SHEN Ju-li;YE Ji-yun;LI Yu-peng(School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University;Department of Journal Editorial of Kunming Medical University,Kunming Yunnan 650500;Advanced Analysis and Measurment Center,Yunnan University,Kunming Yunnan 650091;Dept.of Gynecology,The Third People's Hospital of Yunnan Province,Kunming Yunnan 650011;Laboratory of Microbiology and Immunology,Kunming Medical University,Kunming Yunnan 650500,China)
出处
《昆明医科大学学报》
CAS
2018年第3期1-4,共4页
Journal of Kunming Medical University
基金
supported by grants from the National Natural Science Foundation of China(21202066)
the Natural Science Foundation of Yunnan Province,China[2017FE467(-020),2017FE468(-025)]
the Scientific Research Foundation of Department of Education of Yunnan Province,China(2015Y151,2016ZDX050)
关键词
黄花白及
联苄
菲
二氢菲
Bletilla Ochracea
Bizenzyls
Phenanthrenes
Dihydrophenanthrenes
