抗菌肽在临床生产中的运用

Application of antimicrobial peptides in clinical production

伴随着抗生素在猪饲料中的禁用,所以需要寻找一种能够替代抗生素的药物来维持猪的健康和生产性能。抗菌肽是由植物、昆虫、哺乳动物和微生物产生的天然抗生素,是组成机体免疫系统中的一部分。由于抗菌肽具有广谱的抗微生物活性,包括抑制真菌、细菌和有囊膜病毒等微生物活性,因此,抗菌肽有望代替抗生素应用于猪生产。文章重点阐述抗菌肽的结构和活性机制,以及对猪生产性能、免疫功能和肠道健康的影响。

With the disable on the use of antibiotics in swine feed,so need to be find alternative measures antibiotics medicine to maintain swine health and performance.Antimicrobial peptides(AMPs)are nature antibiotics produced by plants,insects,mammalians and micro-organisms.Due to their broad microbicidal activity against various fungi,bacteria and enveloped viruses,so AMPs are a potential alternative to conventional antibiotics for use in swine production.This review focuses on the structure and mechanism of action of AMPs,as well as their effects on performance,immune function and intestinal health in pigs.