认知护理干预合并集体生物反馈治疗恢复期分裂症顽固性幻听对照研究

Comparative study of cognitive nursing intervention combined with biofeedback therapy in the recovery period of schizophrenia auditory hallucination treatment

目的:观察认知护理干预合并集体生物反馈治疗恢复期精神分裂症患者的顽固性幻听疗效。方法:将120例接受系统抗精神病药物治疗后住院或门诊的恢复期精神分裂症患者,随机分为生物反馈组和认知护理组各60例,认知护理组接受常规认知护理干预,生物反馈组采用认知护理干预合并集体生物反馈治疗,治疗8周;采用阳性阴性症状量表(PANSS)、听幻觉量表(AHRS)、治疗不良反应量表(TESS)分别于治疗前和治疗后第4周、第8周评定疗效和不良反应。结果:治疗4周和8周时PANSS总分和各因子分、听幻觉量表(AHRS)因子评分生物反馈组下降幅度较认知护理组大(P<0.05),生物反馈组临床疗效优于认知护理组(P<0.05);生物反馈组不良反应发生率与认知护理组间比较差异无统计学意义(P>0.05)。结论:采用认知护理干预合并集体生物反馈治疗恢复期精神分裂症患者的顽固性幻听有一定疗效,且安全性好。

Objective:To observe cognitive nursing intervention combined with biofeedback therapy in the recovery period of schizophrenia auditory hallucination treatment.Methods:A total of 120 inpatients or outpatients in the recovery period after schizophrenia auditory hallucination treatment were enrolled and randomly divided into biofeedback group and cognitive nursing group,60 cases in each group.The cognitive nursing group received routine cognitive nursing intervention and the biofeedback group received cognitive nursing intervention combined with the collective biofeedback therapy for 8 weeks.The positive and negative symptoms scale(PANSS),auditory hallucinations scale(AHRS)and Treatment Emergent Symptom Scale(TESS)were adopted to evaluate the curative effect and adverse reactions before and 4 and 8 weeks after the treatment.Results:The decrease of the total and each factor score of ANSS and each factor score of AHRS 4 and 8 weeks after the treatment in the biofeedback group were more significant than those in the cognitive nursing group(P<0.05);the curative effect in the biofeedback group was better than that in the cognitive nursing group(P<0.05);there was no significant difference of adverse reaction rate between the biofeedback group and cognitive nursing group(P>0.05).Conclusion:The cognitive nursing intervention combined with biofeedback therapy in the recovery period of schizophrenia auditory hallucination treatment has certain curative effect,and good safety.